ArticleCell chemical biology2018
Switch of Mitochondrial Superoxide Dismutase into a Prooxidant Peroxidase in Manganese-Deficient Cells and Mice.
Open access · bronzeAbstract read
In one paragraph
Article in Cell chemical biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 55 citations in OpenAlex.
- A mathematical theory of redox biology.Royal Society open science · 2026Article
- A Function-Centric Framework for Mitochondrial Quality Control.Biomolecules · 2026Review
- An intelligent nanoliposome alleviates disc degeneration and discogenic pain by inhibiting neurovascular ingrowth via a "Soil-conditioning, seed-modulating, and weeds-suppressing" strategy.Bioactive materials · 2026Article
- The curious life of human mitochondrial SOD2.International journal of biological macromolecules · 2026Review
- Article
- SOD2 genetics regulating mitochondrial management of oxidative stress is tied to chemical sensitivity in Gulf war veterans.Scientific reports · 2025Article
- Sirtuin-3 promotes osteoclast maturation and bone loss by regulating mitochondrial ROS production during ionizing radiation exposure.JBMR plus · 2025Article
- Gα13 Promotes Clonogenic Growth by Increasing Tolerance to Oxidative Metabolic Stress in Prostate Cancer Cells.International journal of molecular sciences · 2025Article
- Metal Ion Signaling in Biomedicine.Chemical reviews · 2025Review
- Ten "Cheat Codes" for Measuring Oxidative Stress in Humans.Antioxidants (Basel, Switzerland) · 2024Review
- An Overview of Reactive Oxygen Species Damage Occurring during In Vitro Bovine Oocyte and Embryo Development and the Efficacy of Antioxidant Use to Limit These Adverse Effects.Animals : an open access journal from MDPI · 2024Review
- Impact of porous microsponges in minimizing myotoxic side effects of simvastatin.Scientific reports · 2023Article
- Response of the Endogenous Antioxidant Defense System Induced in RAW 264.7 Macrophages upon Exposure to Dextran-Coated Iron Oxide Nanoparticles.Pharmaceutics · 2023Article
- Vitamin D inhibits osteosarcoma by reprogramming nonsense-mediated RNA decay and SNAI2-mediated epithelial-to-mesenchymal transition.Frontiers in oncology · 2023Article
- Predictive modeling of moonlighting DNA-binding proteins.NAR genomics and bioinformatics · 2022Article
- Characterization of ancestral Fe/Mn superoxide dismutases indicates their cambialistic origin.Protein science : a publication of the Protein Society · 2022Article
- Hypoxia aggravates ferroptosis in RPE cells by promoting the Fenton reaction.Cell death & disease · 2022Article
- Nuclear-localized, iron-bound superoxide dismutase-2 antagonizes epithelial lineage programs to promote stemness of breast cancer cells via a histone demethylase activity.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- The Role of Antioxidants in the Interplay between Oxidative Stress and Senescence.Antioxidants (Basel, Switzerland) · 2022Review
- Manganese Superoxide Dismutase Acetylation and Regulation of Protein Structure in Breast Cancer Biology and Therapy.Antioxidants (Basel, Switzerland) · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Douglas GaniniFree Radical Biology Group, Immunity, Inflammation, and Disease Laboratory, NIEHS, NIH, Research Triangle Park, Durham, NC 27709, USA. Electronic address: ganinidasilvad@niehs.nih.gov.
Janine H SantosMammalian Genome Group, Genome Integrity & Structural Biology Laboratory, NIEHS, NIH, Research Triangle Park, Durham, NC 27709, USA.
Marcelo G BoniniDepartments of Medicine and Biophysics, Medical College of Wisconsin, Wauwatosa, WI 53226, USA.
Ronald P MasonFree Radical Biology Group, Immunity, Inflammation, and Disease Laboratory, NIEHS, NIH, Research Triangle Park, Durham, NC 27709, USA. Electronic address: mason4@niehs.nih.gov.
National Institute of Environmental Health Sciences · USMedical College of Wisconsin · USResearch Triangle Park Foundation · US
Funding
Gene Expression and MicroarraysZICES102445 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI GERRISH, KEVIN · 2009 to 2025
$31.6MProtein Derived RadicalsZIAES050139 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI MASON, RONALD P · 2009 to 2018
$17.5MIn Vivo Detection of Free Radical GenerationZIAES050117 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI MASON, RONALD P · 2009 to 2018
$6.9MPROTEIN DERIVED RADICALSZ01ES050139 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI MASON, RONALD P · 1995 to 2008
$4.7MBiomarkers Of Oxidative Stress StudyZIAES048012 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI MASON, RONALD P · 2009 to 2018
$3.0MTRANSITION-METAL MEDIATED FREE RADICAL FORMATION IN VITRO AND IN VIVOZ01ES050117 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI MASON, RONALD P · 1991 to 2008
$2.2MIntramural NIH HHS Z01 ES050117Intramural NIH HHS Z01 ES050139Intramural NIH HHS Z99 ES999999
Abstract
Superoxide radical anion (O
Indexed as
AnimalsHumansHydrogen PeroxideIronManganeseMCF-7 CellsMiceMice, Inbred C57BLMitochondriaOxidative StressPeroxidaseReactive Oxygen SpeciesSuperoxide DismutaseSuperoxide Dismutase 2Hydrogen PeroxideIronManganesePeroxidaseReactive Oxygen SpeciesSuperoxide DismutaseSuperoxide Dismutase 2free radicalsironmanganesemetalsmitochondriamitochondrial metabolismmitochondrial ROSmitochondrial superoxide dismutaseoxidative stressperoxidaseSOD2
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.