Evidence map›Paper›PMID 29398261›Full record

ArticleThe Journal of arthroplasty2018

Prediction Models for 30-Day Mortality and Complications After Total Knee and Hip Arthroplasties for Veteran Health Administration Patients With Osteoarthritis.

Alex Hs Harris, Alfred C Kuo, Thomas Bowe, Shalini Gupta, David Nordin, Nicholas J Giori

Abstract read
In one paragraph

Article in The Journal of arthroplasty, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alex Hs HarrisCenter for Innovation to Implementation, VA Palo Alto Health Care System, Palo Alto, CA; Department of Surgery, Stanford -Surgical Policy Improvement Research and Education Center, Stanford University School of Medicine, Stanford, CA.
Alfred C KuoSan Francisco Veterans Affairs Medical Center, University of California, San Francisco, CA.
Thomas BoweCenter for Innovation to Implementation, VA Palo Alto Health Care System, Palo Alto, CA.
Shalini GuptaCenter for Innovation to Implementation, VA Palo Alto Health Care System, Palo Alto, CA.
David NordinMinneapolis Veterans Affairs Medical Center, Minneapolis, MN.
Nicholas J GioriCenter for Innovation to Implementation, VA Palo Alto Health Care System, Palo Alto, CA; Department of Orthopedic Surgery, Stanford University School of Medicine, Stanford, CA.

Funding

Development and Validation of a Risk Calculator for Total Joint ReplacementI01HX001260 · VA · VETERANS ADMIN PALO ALTO HEALTH CARE SYS · PI KUO, ALFRED C · 2016 to 2025
–
HSRD VA I01 HX001260HSRD VA IK6 HX002840HSRD VA RCS 14-232
6 · The paper itself

Abstract

backgroundStatistical models to preoperatively predict patients' risk of death and major complications after total joint arthroplasty (TJA) could improve the quality of preoperative management and informed consent. Although risk models for TJA exist, they have limitations including poor transparency and/or unknown or poor performance. Thus, it is currently impossible to know how well currently available models predict short-term complications after TJA, or if newly developed models are more accurate. We sought to develop and conduct cross-validation of predictive risk models, and report details and performance metrics as benchmarks.

methodsOver 90 preoperative variables were used as candidate predictors of death and major complications within 30 days for Veterans Health Administration patients with osteoarthritis who underwent TJA. Data were split into 3 samples-for selection of model tuning parameters, model development, and cross-validation. C-indexes (discrimination) and calibration plots were produced.

resultsA total of 70,569 patients diagnosed with osteoarthritis who received primary TJA were included. C-statistics and bootstrapped confidence intervals for the cross-validation of the boosted regression models were highest for cardiac complications (0.75; 0.71-0.79) and 30-day mortality (0.73; 0.66-0.79) and lowest for deep vein thrombosis (0.59; 0.55-0.64) and return to the operating room (0.60; 0.57-0.63).

conclusionsModerately accurate predictive models of 30-day mortality and cardiac complications after TJA in Veterans Health Administration patients were developed and internally cross-validated. By reporting model coefficients and performance metrics, other model developers can test these models on new samples and have a procedure and indication-specific benchmark to surpass.

Indexed as

AgedArthroplasty, Replacement, HipArthroplasty, Replacement, KneeFemaleHospitals, VeteransHumansKnee JointMaleMiddle AgedOsteoarthritis, HipOsteoarthritis, KneePostoperative PeriodPreoperative PeriodRiskUnited StatesVenous Thrombosiscomplicationship arthroplastyinformed consentknee arthroplastymortalitypredictive modelsshared decision-making

Identifiers

PMID29398261
PMCPMC6508537

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.