ArticleCurrent biology : CB2018
A Localized Pseudomonas syringae Infection Triggers Systemic Clock Responses in Arabidopsis.
Article in Current biology : CB, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
26 citing papers in PubMed, 47 citations in OpenAlex.
- The Circadian Clock Regulates Receptor-Mediated Immune Responses to a Herbivore-Associated Molecular Pattern.Plant, cell & environment · 2026Article
- Thermal imaging as a tool for studying circadian rhythms in roots.The Plant journal : for cell and molecular biology · 2026Article
- The KH-domain genes FLK and HOS5 integrate flowering and stress responses in Arabidopsis thaliana.Journal of experimental botany · 2025Article
- High resolution diel transcriptomes of autotetraploid potato reveal expression and sequence conservation among rhythmic genes.BMC genomics · 2025Article
- Circadian clock gene expression: a key player in inflammation underlying chronic lung disease?ERJ open research · 2025Article
- In vivo dynamics of indole- and phenol-derived plant hormones: Long-term, continuous, and minimally invasive phytohormone sensor.Science advances · 2025Article
- Crosstalk between salicylic acid signalling and the circadian clock promotes an effective immune response in plants.Npj biological timing and sleep · 2024Article
- Light prevents pathogen-induced aqueous microenvironments via potentiation of salicylic acid signaling.Nature communications · 2023Article
- Environment-mediated mutagenetic interference on genetic stabilization and circadian rhythm in plants.Cellular and molecular life sciences : CMLS · 2022Review
- Circadian rhythms in infectious diseases and symbiosis.Seminars in cell & developmental biology · 2022Review
- Evaluating the Effects of the Circadian Clock and Time of Day on Plant Gravitropic Responses.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Review
- Plant Immune Mechanisms: From Reductionistic to Holistic Points of View.Molecular plant · 2020Review
- Coronatine is more potent than jasmonates in regulating Arabidopsis circadian clock.Scientific reports · 2020Article
- Chemical Perturbation of Chloroplast-Related Processes Affects Circadian Rhythms of Gene Expression inFrontiers in physiology · 2020Article
- Recent advances in understanding regulation of the Arabidopsis circadian clock by local cellular environment.F1000Research · 2020Review
- Plant-Microbe Interactions Facing Environmental Challenge.Cell host & microbe · 2019Review
- Bacterial infection systemically suppresses stomatal density.Plant, cell & environment · 2019Article
- Host circadian rhythms are disrupted during malaria infection in parasite genotype-specific manners.Scientific reports · 2019Article
- LUX ARRHYTHMO mediates crosstalk between the circadian clock and defense in Arabidopsis.Nature communications · 2019Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
The circadian clock drives daily rhythms of many plant physiological responses, providing a competitive advantage that improves plant fitness and survival rates [1-5]. Whereas multiple environmental cues are predicted to regulate the plant clock function, most studies focused on understanding the effects of light and temperature [5-8]. Increasing evidence indicates a significant role of plant-pathogen interactions on clock regulation [9, 10], but the underlying mechanisms remain elusive. In Arabidopsis, the clock function largely relies on a transcriptional feedback loop between morning (CCA1 and LHY)- and evening (TOC1)-expressed transcription factors [6-8]. Here, we focused on these core components to investigate the Arabidopsis clock regulation using a unique biotic stress approach. We found that a single-leaf Pseudomonas syringae infection systemically lengthened the period and reduced the amplitude of circadian rhythms in distal uninfected tissues. Remarkably, the low-amplitude phenotype observed upon infection was recapitulated by a transient treatment with the defense-related phytohormone salicylic acid (SA), which also triggered a significant clock phase delay. Strikingly, despite SA-modulated circadian rhythms, we revealed that the master regulator of SA signaling, NPR1 [11, 12], antagonized clock responses triggered by both SA treatment and P. syringae. In contrast, we uncovered that the NADPH oxidase RBOHD [13] largely mediated the aforementioned clock responses after either SA treatment or the bacterial infection. Altogether, we demonstrated novel and unexpected roles for SA, NPR1, and redox signaling in clock regulation by P. syringae and revealed a previously unrecognized layer of systemic clock regulation by locally perceived environmental cues.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.