Evidence map›Paper›PMID 29397537›Full record

ArticleInfection2018

Management of bloodstream infections by infection specialists in France and Germany: a cross-sectional survey.

Kévin Diallo, Winfried V Kern, Katja de With, Amandine Luc, Nathalie Thilly, Céline Pulcini, ESGAP and ESGBIS

Registry-linked trialAbstract read
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In one paragraph

Article in Infection, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04070820 ("Combination Treatment for Enterococcus Faecalis Bacteremia), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04070820 unknown statusnot on this mapstarted 2019, after this paper: background citation

"Combination Treatment for Enterococcus Faecalis Bacteremia: a Prospective, Multicenter, Observational Study"

TypeobservationalSponsorUniversity of BolognaRan2019 to 2021Enrolled500ConditionsEnterococcal Bacteraemia, Enterococcus Faecalis Infection, Enterococcal Endocarditis, Bloodstream Infection
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Short course of antimicrobial treatment for uncomplicated enterococcal bacteremia.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kévin DialloService de Maladies Infectieuses et Tropicales, Centre Hospitalier Universitaire de Nancy, Hôpitaux de Brabois, allée du Morvan, 54511, Vandoeuvre-Lès-Nancy, France.
Winfried V KernDivision of Infectious Diseases, Department of Medicine II, University of Freiburg Faculty of Medicine and Medical Center, Freiburg, Germany.
Katja de WithDivision of Infectious Disease, University Hospital Carl Gustav Carus at the TU Dresden Medical Center, Dresden, Germany.
Amandine LucCHRU de Nancy, Plateforme d'Aide à la Recherche Clinique, Nancy, France.
Nathalie ThillyCHRU de Nancy, Plateforme d'Aide à la Recherche Clinique, Nancy, France.
Céline PulciniService de Maladies Infectieuses et Tropicales, Centre Hospitalier Universitaire de Nancy, Hôpitaux de Brabois, allée du Morvan, 54511, Vandoeuvre-Lès-Nancy, France. celine.pulcini@univ-lorraine.fr.
ESGAP and ESGBIS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionBloodstream infections (BSI) are frequent infections worldwide. Our objective was to explore variation in the management of patients with BSI by infection specialists in France and Germany.

methodsThis work is part of an international ESCMID cross-sectional internet-based questionnaire survey that was opened from December 2016 to February 2017. All hospital-based infection specialists, senior or trainees, giving at least weekly advice on positive blood cultures could participate. Their practices were evaluated using six clinical vignettes presenting an uncomplicated BSI due to different pathogens.

resultsA hundred and ninety-six professionals (125 from Germany and 71 from France) participated. Systematic expert advice for positive blood cultures was more often available in Germany as compared with France (73 vs. 56%, p = 0.004). In Germany, the professional providing the expert advice was more often a microbiologist or a pharmacist as compared with France (p = 0.001 and p = 0.037, respectively) where it was more often an infectious diseases specialist. Fewer German respondents reported to advise systematic IV-oral switch of antibiotic therapy. German respondents also recommended less often combination therapy: for example for Enterococcus faecalis (64 vs. 43%, p = 0.015), ESBL E. coli (94 vs. 67%, p < 0.001) and Pseudomonas aeruginosa (76 vs. 37%, p < 0.001). Overall, management of candidaemia was more often compliant with the IDSA guidelines in France as compared with Germany, but no difference was noted for MRSA bacteraemia.

conclusionOur survey shows that wide variations exist between two neighboring countries in the recommendations by infection specialists for the management of BSI. International guidelines are needed.

Indexed as

AdultAnti-Infective AgentsBacteremiaCross-Sectional StudiesFemaleFranceGermanyHospitalsHumansInfectious Disease MedicineMaleMiddle AgedPhysiciansAnti-Infective AgentsAntibiotic stewardshipBacteraemiaBlood cultureCandidaemiaQuestionnaireSurvey

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.