Evidence map›Paper›PMID 29397535›Full record

ArticleNeurochemical research2018

The Leptin, Dopamine and Serotonin Receptors in Hypothalamic POMC-Neurons of Normal and Obese Rodents.

Irina V Romanova, Kira V Derkach, Anastasiya L Mikhrina, Ivan B Sukhov, Elena V Mikhailova, Alexander O Shpakov

Abstract read
PubMed Publisher
In one paragraph

Article in Neurochemical research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 73 citations in OpenAlex.

  1. Pooled it
  2. The Genetic Blueprint of Obesity: From Pathogenesis to Novel Therapies.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025
    Review
  3. Biological mechanisms of dopamine DFrontiers in endocrinology · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Orexin, serotonin, and energy balance.WIREs mechanisms of disease · 2022
    Review
  13. Dopaminergic Control of the Feeding Circuit.Endocrinology and metabolism (Seoul, Korea) · 2021
    Review
  14. Review
  15. Article
  16. Review
  17. Glucagon-Like Peptide-1 (GLP-1) and 5-Hydroxytryptamine 2c (5-HTInternational journal of molecular sciences · 2019
    Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Irina V RomanovaI.M. Sechenov Institute of Evolutionary Physiology and Biochemistry of Russian Academy of Sciences, Saint Petersburg, Russia. irinaromanova@mail.ru.ORCID http://orcid.org/0000-0002-0348-0631
Kira V DerkachI.M. Sechenov Institute of Evolutionary Physiology and Biochemistry of Russian Academy of Sciences, Saint Petersburg, Russia.
Anastasiya L MikhrinaI.M. Sechenov Institute of Evolutionary Physiology and Biochemistry of Russian Academy of Sciences, Saint Petersburg, Russia.
Ivan B SukhovI.M. Sechenov Institute of Evolutionary Physiology and Biochemistry of Russian Academy of Sciences, Saint Petersburg, Russia.
Elena V MikhailovaI.M. Sechenov Institute of Evolutionary Physiology and Biochemistry of Russian Academy of Sciences, Saint Petersburg, Russia.
Alexander O ShpakovI.M. Sechenov Institute of Evolutionary Physiology and Biochemistry of Russian Academy of Sciences, Saint Petersburg, Russia.
Institute of Evolutionary Physiology and Biochemistry · RU

Funding

Russian Science Foundation 16-15-10388
6 · The paper itself

Abstract

The pro-opiomelanocortin (POMC)-expressing neurons of the hypothalamic arcuate nucleus (ARC) are involved in the control of food intake and metabolic processes. It is assumed that, in addition to leptin, the activity of these neurons is regulated by serotonin and dopamine, but only subtype 2C serotonin receptors (5-HT

Indexed as

AnimalsFemaleHypothalamusMaleMiceMice, Inbred C57BLNeuronsObesityPro-OpiomelanocortinRatsRats, WistarReceptors, DopamineReceptors, LeptinReceptors, SerotoninRodentiaPro-OpiomelanocortinReceptors, DopamineReceptors, LeptinReceptors, SerotoninAgouti miceDopamineHypothalamusLeptinObesityPOMC neuronPro-opiomelanocortinSerotonin

Identifiers

PMID29397535
OpenAlexW2793542242

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.