Evidence map›Paper›PMID 29397430›Full record

ArticleInternational journal of colorectal disease2018

Long-term quality of life after conservative treatment versus surgery for different stages of acute sigmoid diverticulitis.

Martina Brandlhuber, Christian Genzinger, Bernhard Brandlhuber, Wieland H Sommer, Mario H Müller, Martin E Kreis

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in International journal of colorectal disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Guideline
  2. Pooled it
  3. [Indications for surgical treatment of diverticular disease].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2021
    Review
  4. Changing Paradigms in the Management of Acute Uncomplicated Diverticulitis.Scandinavian journal of surgery : SJS : official organ for the Finnish Surgical Society and the Scandinavian Surgical Society · 2021
    Review
  5. Article
  6. Observational
  7. Review
  8. Elective Laparoscopic Sigmoid Colectomy for Diverticulitis-an Updated Look at Recurrence After Surgery.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2020
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Martina BrandlhuberDepartment of Radiology, Ludwig Maximilian University of Munich, Marchionini Str. 15, 81377, Munich, Germany.
Christian GenzingerDepartment of Anesthesiology, Ludwig Maximilian University of Munich, Marchionini Str. 15, 81377, Munich, Germany.
Bernhard BrandlhuberDepartment of Internal Medicine, Klinik Mühldorf am Inn, Krankenhausstraße 1, 84453, Mühldorf am Inn, Germany.
Wieland H SommerDepartment of Radiology, Ludwig Maximilian University of Munich, Marchionini Str. 15, 81377, Munich, Germany.
Mario H MüllerDepartment of Visceral Surgery, Vivantes Klinikum Neukölln, Rudower Straße 48, 12351, Berlin, Germany.
Martin E KreisDepartment of General-, Visceral- and Vascular Surgery, Charité University Medicine Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12200, Berlin, Germany. martin.kreis@charite.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIt is controversial whether patients fare better with conservative or surgical treatment in certain stages of acute diverticulitis (AD), in particular when phlegmonous inflammation or covered micro- or macro-perforation are present. The aim of this study was to determine long-term quality of life (QoL) for AD patients who received either surgery or conservative treatment in different stages.

methodsWe included patients treated for AD at the University Hospital Grosshadern, Munich, Germany, between January 1, 2000, and December 31, 2010. Patients were classified by the Hansen and Stock (HS) classification, the modified Hinchey classification, and the German classification of diverticular disease (CDD). Pre-therapeutic staging was based on multidetector computed tomography. Long-term QoL was assessed by the Cleveland Global Quality of Life (CGQL) questionnaire, the Short Form 36 (SF-36), and the Gastrointestinal Quality of Life Index (GIQLI). Data are mean ± SEM.

resultsPatients with phlegmonous AD (HS type 2a, Hinchey Ia and CDD 1b, respectively) had a better long-term QoL on the GIQLI when they were operated (78.5 ± 2.5 vs. 70.7 ± 2.1; p < 0.05). Patients with micro-abscess (CDD 2a) had a better long-term QoL on the GIQLI, CGQL, and the "Role Physical" scale of the SF-36 when they were not operated (GIQLI 86.9 ± 2.1 vs. 76.8 ± 1.0; p = 0.10; CGQL 82.8 ± 5.1 vs. 65.3 ± 11.0; p = 0.08; SF-36/Role Physical 100 ± 0.0 vs. 41.7 ± 13.9; p < 0.001). Patients with macro-abscess (CDD 2b) had a better long-term QoL when they were operated (GIQLI 89.3 ± 1.4 vs. 69.5 ± 4.5; p < 0.01; CGQL 80.3 ± 7.6 vs. 60.5 ± 5.8; p < 0.05; SF-36/Role Physical 95.8 ± 4.2 vs. 47.9 ± 13.6; p < 0.001).

conclusionConsidering long-term QoL, phlegmonous AD (HS type 2a, Hinchey Ia and CDD 1b, respectively) should be treated conservatively. In patients with covered perforation, abscess size should guide the decision on whether to perform surgery later on or not. In the light of long-term quality of life, patients fare better after elective sigmoid colectomy when abscess size exceeds 1 cm.

Indexed as

Conservative TreatmentQuality of LifeAcute DiseaseAdultAgedAged, 80 and overColon, SigmoidDiverticulitisDocumentationFemaleHumansInterviews as TopicMaleMiddle AgedReproducibility of ResultsSurveys and QuestionnairesDiverticular diseaseGerman classification of diverticular diseaseHansen and stock classificationQuality of lifeSigmoid diverticulitis

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.