ArticleBiological psychiatry. Cognitive neuroscience and neuroimaging2018
Time-Frequency Reward-Related Delta Prospectively Predicts the Development of Adolescent-Onset Depression.
Article in Biological psychiatry. Cognitive neuroscience and neuroimaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.
- Neuroimaging predictors of onset and course of depression in childhood and adolescence: A systematic review of longitudinal studies.Developmental cognitive neuroscience · 2019Pooled it
- Brain rhythms of depression: A predictive processing perspective.Trends in neurosciences · 2026Review
- Neural Responses to Reward and Psychosis Dimensions.Schizophrenia bulletin · 2026Article
- Childhood P300 predicts development of depressive disorders into adolescence.Cognitive, affective & behavioral neuroscience · 2026Article
- Intracranial directed connectivity links subregions of the prefrontal cortex to major depression.Nature communications · 2025Article
- Neuroimaging findings of adolescent depression: A review by the Research Domain Criteria (RDoC) framework.Psychiatry research. Neuroimaging · 2025Review
- Attenuated Doors-Locked P300 Amplitude and Elevated Depressive Symptoms: Effects of Age and Sex in Two Independent Samples of Youth.Psychophysiology · 2025Article
- Atypical reward anticipation in impulsive individuals: evidence from EEG and experiential delay discounting.Frontiers in psychology · 2025Article
- Intracranial Directed Connectivity Links Subregions of the Prefrontal Cortex to Major Depression.medRxiv : the preprint server for health sciences · 2024Article
- Reduced approach disposition in familial risk for depression: Evidence from time-frequency alpha asymmetries.PloS one · 2024Article
- Deficits in doors P300 amplitude during adolescence associated with preschool-onset depression.Psychophysiology · 2023Article
- Characterizing positive and negative valence systems function in adolescent depression: An RDoC-informed approach integrating multiple neural measures.Journal of mood and anxiety disorders · 2023Article
- Preliminary evidence that individuals with remitted alcohol use disorder and major depressive disorder exhibit enhanced neural responses to reward: An EEG study.Addictive behaviors · 2023Article
- Rethinking the risk for depression using the RDoC: A psychophysiological perspective.Frontiers in psychology · 2023Review
- EEG time-frequency analysis reveals blunted tendency to approach and increased processing of unpleasant stimuli in dysphoria.Scientific reports · 2022Article
- Time-frequency analysis methods and their application in developmental EEG data.Developmental cognitive neuroscience · 2022Article
- Depressive Symptoms Prospectively Predict Peer Victimization: A Longitudinal Study Among Adolescent Females.Child psychiatry and human development · 2022Article
- Win, lose, or draw: Examining salience, reward memory, and depression with the reward positivity.Psychophysiology · 2022Article
- What Event-Related Potential Tells Us about Brain Function: Child-Adolescent Psychiatric Perspectives.Soa--ch'ongsonyon chongsin uihak = Journal of child & adolescent psychiatry · 2021Review
- Reward Functioning Abnormalities in Adolescents at High Familial Risk for Depressive Disorders.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundA blunted reward positivity (RewP), an event-related potential elicited by feedback indicating monetary gain relative to loss, was recently shown to prospectively predict the development of adolescent-onset depression. Time-frequency-based representations of this activity (e.g., reward-related delta) have also been associated with depression. This study is a reanalysis of the time-domain RewP investigation to examine the incremental value of time-frequency indices in the prediction of adolescent-onset depression.
methodsThe sample included 444 13- to 15-year-old girls with no lifetime history of a depressive disorder. At baseline, adolescents completed a monetary guessing task, and both time-domain and time-frequency analyses were conducted on the event-related potential response to gain and loss feedback. Lifetime psychiatric history in the adolescent and a biological parent were evaluated with diagnostic interviews, and adolescents' current depressive symptoms were assessed using a self-report questionnaire. Adolescents were interviewed again approximately 18 months later to identify first-onset depressive disorder.
resultsBlunted reward-related delta predicted first-onset depressive disorder 18 months later, independent of the time-domain RewP and psychosocial risk factors (i.e., adolescent baseline depressive symptoms, adolescent and parental psychiatric history). In contrast, loss-related theta did not predict the development of depression. Reward-related delta increased sensitivity (73.8% to 82.8%) and positive predictive value (45.0% to 70.9%) for first-onset depressive disorder when applied in parallel and in series, respectively, with baseline depressive symptoms and the time-domain RewP.
conclusionsThis study provides evidence that frequency-based representations of event-related potentials provide incremental value in the prediction of psychiatric disorders.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.