ArticleEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2019
Epidemiology of open tibia fractures in a population-based database: update on current risk factors and clinical implications.
Article in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06976801 (Prospective, Randomized-control Trial Comparing Standard Intramedullary Tibial Fixation With Micromotion Tibial Intramedullary Fixation), which is not on this map. Cited by 29 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Prospective, Randomized-control Trial Comparing Standard Intramedullary Tibial Fixation With Micromotion Tibial Intramedullary Fixation
Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 77 citations in OpenAlex.
- Plating as a reduction aid prior to intramedullary nailing of tibia fractures: a systematic review and meta-analysis.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2024Pooled it
- Medullary cavity application of tranexamic acid to reduce blood loss in tibial intramedullary nailing procedures-a randomized controlled trial.International orthopaedics · 2023Trial
- Experimental justification for the use of the artificial deformity creation method for the treatment of patients with extensive soft tissue defects.OTA international : the open access journal of orthopaedic trauma · 2026Article
- Outcomes of Primary Definitive Internal Fixation of Compound Fractures within 72 h of Injury: A Prospective Cohort Study.Journal of orthopaedic case reports · 2026Article
- A Linked Population-Based Analysis of Severe Lower Extremity Traumas in Ontario.Plastic surgery (Oakville, Ont.) · 2025Article
- Article
- Open Tibial Fractures Part 1: A Narrative Review of Initial Treatment and Potential Applicability to the Southern African Context.Orthopedic research and reviews · 2025Review
- Article
- Treatment of Diaphyseal Tibial Non-unions After Open Fracture: A Retrospective Observational Study on Characteristics and Outcomes.Indian journal of orthopaedics · 2024Article
- Atypical Tibial Fracture Following Chronic Bisphosphonate Use: A Case Report and Review of the Literature.Cureus · 2024Article
- Heparin-Induced Thrombocytopenia After Revascularization of Gustilo-Anderson Type IIIC Open Lower Leg Fracture: A Case Report of Subsequent Ischemic Limb Salvage Failure.The American journal of case reports · 2024Article
- Classification of open tibia fractures: the rationale for a new classification system.OTA international : the open access journal of orthopaedic trauma · 2024Review
- Negative Pressure Wound Therapy versus Conventional Dressing in Lower Limb Fractures: Systematic Review and Meta-analysis.Plastic and reconstructive surgery. Global open · 2024Article
- TIME UNTIL THE START OF ANTIBIOTIC PROPHYLAXIS AND THE RISK OF OPEN FRACTURE INFECTION: A SYSTEMATIC REVIEW.Acta ortopedica brasileira · 2024Review
- Smokeless Tobacco Use is Associated with Worse Outcomes Following Open Tibia Fracture.Orthopedic reviews · 2024Article
- Predictors for infection severity for open tibial fractures: major trauma centre perspective.Archives of orthopaedic and trauma surgery · 2023Article
- The relevance of the number of distal locking planes and nail to canal ratio in bone healing after intramedullary nailing in tibial shaft fractures.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2023Article
- Comparison of antibiotic-impregnated bone cement coverage versus vacuum sealing drainage in semi-open bone grafting using for tibial fracture with infected bone and soft tissue defect: a retrospective analysis.BMC musculoskeletal disorders · 2023Article
- Musculoskeletal injuries in trauma patients: a Swedish nationwide register study including 37,266 patients.Acta orthopaedica · 2023Article
- Epidemiology of Open Tibia fractures presenting to a tertiary referral centre in Southern Malawi: a retrospective study.Malawi medical journal : the journal of Medical Association of Malawi · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOpen tibia fractures usually occur in high-energy mechanisms and are commonly associated with multiple traumas. The purposes of this study were to define the epidemiology of open tibia fractures in severely injured patients and to evaluate risk factors for major complications.
methodsA cohort from a nationwide population-based prospective database was analyzed (TraumaRegister DGU
resultsOut of 148.498 registered patients between 1/2002 and 12/2013; a total of 4.940 met the inclusion criteria (mean age 46.2 ± 19.4 years, ISS 30.4 ± 12.6 points). The CTF group included 2000 patients (40.5%), whereas 2940 patients (59.5%) sustained open tibia fractures (I°: 49.3%, II°: 27.5%, III°: 23.2%). High-energy trauma was the leading mechanism in case of open fractures. Despite comparable ISS and NISS values in patients with closed and open tibia fractures, open fractures were significantly associated with higher volume resuscitation (p < 0.001), more blood (p < 0.001), and mass transfusions (p = 0.006). While the rate of external fixation increased with the severity of soft tissue injury (37.6 to 76.5%), no major effect on mortality and other major complications was observed.
conclusionOpen tibia fractures are common in multiple trauma patients and are therefore associated with increased resuscitation requirements, more surgical procedures and increased in-hospital length of stay. However, increased systemic complications are not observed if a soft tissue adapted surgical protocol is applied.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.