ArticleJournal of neurology2018
Cerebellum and cognition in multiple sclerosis: the fall status matters.
Article in Journal of neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed.
- Cerebellar Volume Measures Differentiate Multiple Sclerosis Fallers from Non-Fallers.Brain sciences · 2025Article
- Cerebellar volume measures may differentiate multiple sclerosis fallers from non-fallers.Research square · 2024Article
- Exploring Factors Associated with Falls in Multiple Sclerosis: Insights from a Scoping Review.Clinical interventions in aging · 2024Article
- Fall risk is related to cognitive functioning in ambulatory multiple sclerosis patients.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023Article
- Cerebellar Contributions to Motor and Cognitive Control in Multiple SclerosisArchives of physical medicine and rehabilitation · 2022Article
- Dalfampridine improves slowed processing speed in multiple sclerosis patients with mild motor disability: post hoc analysis of a randomized controlled trial.Therapeutic advances in neurological disorders · 2021Article
- Occulomotor Neural Integrator Dysfunction in Multiple Sclerosis: Insights From Neuroimaging.Frontiers in neurology · 2018Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cerebellar volume has been linked with cognitive performances in MS; however, the association in terms of fall status has never been compared. Therefore, the objective of the current study was to compare cognitive performance with cerebellar volume between MS fallers and non-fallers. The cross-sectional study included 140 PwMS (96 women). MRI volumetric analysis was based on the FreeSurfer image analysis suite. Volumes of the cerebellar gray and white matter were identified as the region of interest. Cognitive function included scores obtained from a computerized cognitive battery of tests. The sample was divided into fallers and non-fallers. MS fallers demonstrated a lower global cognitive performance and reduced gray and white matter cerebellar volumes compared to non-fallers. A significant association was found between total gray and white matter cerebellar volume and visual spatial subdomain (P value = 0.044 and 0.032, respectively) in the non-fallers group. The association remained significant after controlling for the total cranial volume and neurological disability (P value = 0.026 and 0.047, respectively). A relationship was found between the visual spatial score and the left gray matter cerebellum volume; R
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.