Evidence map›Paper›PMID 29396662›Full record

Trial reportGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2018

MiSight Assessment Study Spain (MASS). A 2-year randomized clinical trial.

Alicia Ruiz-Pomeda, Belén Pérez-Sánchez, Isabel Valls, Francisco Luis Prieto-Garrido, Ramón Gutiérrez-Ortega, César Villa-Collar

2 registry-linked trialsAbstract readComparative StudyRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 77 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed, 7 pooled it
11.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01917110 nacompletednot on this map

Efficacy and Safety of MiSight ® Contact Lenses in Reducing the Progression of Childhood Myopia, Not Pathological, Aged 8-12 Years Randomized Clinical Trial.

TypeinterventionalSponsorCooperVision, Inc.Ran2013 to 2016Enrolled79ConditionsMyopiaArmsomafilcon A, Spectacle
NCT05955638 naenrolling by invitationnot on this mapstarted 2024, after this paper: background citation

Management of Myopia in University Students Using Dual Focus Soft Contact Lenses

TypeinterventionalSponsorUniversity of BradfordRan2024 to 2028Enrolled84ConditionsMyopia, ProgressiveArmsMiSight contact lenses, Proclear contact lenses
3 · Its place in the literature

Who cites it

77 citing papers in PubMed, 7 syntheses or guidelines pooled it, 174 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Guideline
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  5. Pooled it
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  7. Interventions to slow progression of myopia in children.The Cochrane database of systematic reviews · 2020
    Pooled it
  8. Clinical evaluation of MyoCare in Europe (CEME) for myopia management: One-year results.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2025
    Trial
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  10. [Visual Performance of School-age Children Wearing Dual-Focus Soft Contact Lenses: A Randomized Controlled Trial].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2024
    Trial
  11. Trial
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  14. Short-term tear film stability, optical quality and visual performance in two dual-focus contact lenses for myopia control with different optical designs.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2022
    Trial
  15. Trial
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  17. Adverse event rates in the retrospective cohort study of safety of paediatric soft contact lens wear: the ReCSS study.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2021
    Trial
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  20. Myopia control with novel central and peripheral plus contact lenses and extended depth of focus contact lenses: 2 year results from a randomised clinical trial.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2019
    Trial

17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Alicia Ruiz-PomedaDepartment of Pharmacy, Biotechnology, Optics and Optometry, European University of Madrid, C/Tajo s/n, Villaviciosa de Odón, 28670, Madrid, Spain. alicia.ruiz@universidadeuropea.es.ORCID http://orcid.org/0000-0002-8318-5914
Belén Pérez-SánchezDepartment of Statistics, Mathematics and Informatics. Area of Languages and Computer Systems, Miguel Hernández University of Elche, Elche, Alicante, Spain.
Isabel VallsClínica oftalmológica Novovision, Madrid, Spain.
Francisco Luis Prieto-GarridoDepartment Optics I: Optometry and Vision, Universidad Complutense de Madrid, Madrid, Spain.
Ramón Gutiérrez-OrtegaClínica oftalmológica Novovision, Madrid, Spain.
César Villa-CollarDoctoral and Research School, European University of Madrid, Madrid, Spain.
Clínica Rementería · ESUniversidad Europea de Madrid · ESUniversidad Complutense de Madrid · ESUniversitat de Miguel Hernández d'Elx · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare myopia progression in children randomized to MiSight contact lenses (CLs) versus children corrected with single-vision spectacles (SV) over a 2-year period.

methodsSubjects aged 8 to 12 with myopia (-0.75 to -4.00 D sphere) and astigmatism (< -1.00 D cylinder) were assigned to the lens study group (MiSight) or the control group (single vision). Measurements of visual acuity and subjective refraction were taken at 6-month intervals, and axial length, anterior chamber, corneal power, and cycloplegic autorefraction were measured at the baseline, 12-month, and 24-month visits.

resultsEighty-nine subjects were recruited. Forty-fix children were assigned to the MiSight group, and 33 to the single-vision spectacle group. In total, 74 children completed the clinical trial, with the following parameters at the beginning of the study: n =  41 in the MiSight group (age: 11.01 ± 1.23 years, spherical equivalent: -2.16 ± 0.94 D, gender: male: 21, female: 20) and n = 33 in the single-vision group (age: 10.12 ± 1.38 years, spherical equivalent: -1.75 ± 0.94 D, gender: male: 12, female: 21). After 2 years of follow-up, myopia progressed slowly in the MiSight group compared to the control group (0.45 D vs 0.74 D, p < 0.001) and there was less axial elongation in the MiSight group compared to the single-vision group (0.28 mm vs 0.44 mm, p < 0.001). Therefore, use of MiSight CLs produced lower myopia progression (39.32%) and lower axial growth of the eye (36.04%) at 2 years compared to spectacle use.

conclusionsMiSight contact lens wear reduces axial elongation and myopia progression in comparison to distance single-vision spectacles in children. ClinicalTrials.gov Identifier: NCT01917110.

Indexed as

Contact Lenses, HydrophilicEyeglassesAxial Length, EyeChildDisease ProgressionFemaleHumansMaleMyopiaRefraction, OcularSpainVision, BinocularVision TestsVisual AcuityAxial lengthChildrenContact lensesMiSightMyopia

Identifiers

PMID29396662
OpenAlexW2786119475

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.