ArticlePharmaceutical research2018
Cocrystal Solubility Product Prediction Using an in combo Model and Simulations to Improve Design of Experiments.
Article in Pharmaceutical research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 23 citations in OpenAlex.
- From Solution to Sublimation: Thermodynamic Evaluation of Iproniazid Multicomponent Crystals for Robust Pharmaceutical Solid Form Development.Pharmaceutical research · 2026Article
- Often neglected steps in transforming drug solubility from single measurement in pure water to physiologically-appropriate solubility-pH.ADMET & DMPK · 2025Article
- New Lidocaine-Based Pharmaceutical Cocrystals: Preparation, Characterization, and Influence of the Racemic vs. Enantiopure Coformer on the Physico-Chemical Properties.Pharmaceutics · 2023Article
- Formation Thermodynamics of Carbamazepine with Benzamide, Para-Hydroxybenzamide and Isonicotinamide Cocrystals: Experimental and Theoretical Study.Pharmaceutics · 2022Article
- Perspectives in solubility measurement and interpretation.ADMET & DMPK · 2019Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo predict the aqueous solubility product (K
methodA regression model was constructed, assuming that the concentration of the uncharged drug (API) can be nearly equated to drug intrinsic solubility (S
resultsThe optimal model found for n:1 CCs (-log
conclusionThe predicted CC K
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.