Evidence map›Paper›PMID 29396591›Full record

SynthesisAesthetic plastic surgery2018

Clinical Application of Platelet-Rich Fibrin in Plastic and Reconstructive Surgery: A Systematic Review.

Panxi Yu, Zhen Zhai, Xiaolei Jin, Xiaonan Yang, Zuoliang Qi

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Aesthetic plastic surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
7.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Review
  15. Autologous platelet concentrates for facial rejuvenation.Journal of applied oral science : revista FOB · 2022
    Review
  16. Article
  17. Article
  18. Blood-Derived Biomaterial for Catheter-Directed Arterial Embolization.Advanced materials (Deerfield Beach, Fla.) · 2020
    Article
  19. Autologous platelet concentrates in maxillofacial regenerative therapy.The Kaohsiung journal of medical sciences · 2020
    Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Panxi YuThe 16th Department, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College (CAMS, PUMC), 33 Badachu Road, Shijingshan District, Beijing, 100144, China.
Zhen ZhaiThe 16th Department, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College (CAMS, PUMC), 33 Badachu Road, Shijingshan District, Beijing, 100144, China.
Xiaolei JinThe 16th Department, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College (CAMS, PUMC), 33 Badachu Road, Shijingshan District, Beijing, 100144, China.
Xiaonan YangThe 16th Department, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College (CAMS, PUMC), 33 Badachu Road, Shijingshan District, Beijing, 100144, China. yxnan@aliyun.com.
Zuoliang QiThe 16th Department, Plastic Surgery Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College (CAMS, PUMC), 33 Badachu Road, Shijingshan District, Beijing, 100144, China. public_qi@163.com.
Chinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

Research Innovation Program for Graduates of Chinese Academy of Medical Sciences and Peking Union Medical College 2017-1002-2-08
6 · The paper itself

Abstract

backgroundPlatelet-rich fibrin (PRF) has been applied in the clinical field for more than a decade, but largely in oral surgery and implant dentistry. Its utilization in plastic and reconstructive surgery is limited and lacking a comprehensive review. Hence, this article focuses on the various clinical applications of PRF pertaining to the plastic and reconstructive field through a systematic review.

methodsIn this review, articles describing the clinical application of PRF in plastic and reconstructive surgery were screened using predetermined inclusion and exclusion criteria. The articles were summarized and divided into groups based on the utilization of PRF. The effects and complications of PRF were analyzed and concluded.

resultsAmong the 634 articles searched, 7 articles describing 151 cases are eligible. PRF was applied on 116 (76.8%) wounds to facilitate tissue healing, and the complete wound closure rate was 91.4% (106/116). Otherwise, PRF was applied in 10 (6.6%) cases of zygomaticomaxillary fracture to reconstruct orbital floor defects and in 25 (16.6%) cases of facial autologous fat grafts to increase the fat retention rate successfully. There is no report of PRF-related complications.

conclusionsPRF could facilitate wound healing, including the healing of soft tissues and bony tissues, and facilitate fat survival rate. Further studies are needed to test the mechanism of PRF and expand its scope of application in plastic and reconstructive surgery. LEVEL OF EVIDENCE III: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .

Indexed as

Platelet-Rich FibrinChinaFemaleHumansMalePlastic Surgery ProceduresPrognosisSurgery, PlasticWound HealingClinical applicationPlastic and reconstructive surgeryPRF

Identifiers

PMID29396591
OpenAlexW2787595633

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.