Evidence map›Paper›PMID 29396560›Full record

Trial reportScientific reports2018

Dynamic changes of phenotypically different circulating tumor cells sub-populations in patients with recurrent/refractory small cell lung cancer treated with pazopanib.

Ippokratis Messaritakis, Eleni Politaki, Fillipos Koinis, Dimitris Stoltidis, Stella Apostolaki, Maria Plataki, Eleftheria-Kleio Dermitzaki, Vassilis Georgoulias, Athanasios Kotsakis

Open access · goldAbstract readClinical Trial, Phase IIMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Ippokratis MessaritakisLaboratory of Tumor Cell Biology, Medical School, University of Crete, Heraklion, Crete, Greece.
Eleni PolitakiLaboratory of Tumor Cell Biology, Medical School, University of Crete, Heraklion, Crete, Greece.
Fillipos KoinisLaboratory of Tumor Cell Biology, Medical School, University of Crete, Heraklion, Crete, Greece.
Dimitris StoltidisDepartment of Medical Oncology, University General Hospital of Heraklion, Crete, Greece.
Stella ApostolakiLaboratory of Tumor Cell Biology, Medical School, University of Crete, Heraklion, Crete, Greece.
Maria PlatakiLaboratory of Tumor Cell Biology, Medical School, University of Crete, Heraklion, Crete, Greece.
Eleftheria-Kleio DermitzakiDepartment of Medical Oncology, University General Hospital of Heraklion, Crete, Greece.
Vassilis GeorgouliasLaboratory of Tumor Cell Biology, Medical School, University of Crete, Heraklion, Crete, Greece. georgoul@uoc.gr.
Athanasios KotsakisLaboratory of Tumor Cell Biology, Medical School, University of Crete, Heraklion, Crete, Greece.
University of Crete · GRUniversity Hospital of Heraklion · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the study was to investigate the effect of 2

Indexed as

AdultAgedAged, 80 and overAngiogenesis InhibitorsAntineoplastic AgentsBiomarkers, TumorCell CountCell Line, TumorFemaleFluorescent Antibody TechniqueHeLa CellsHumansIndazolesLung NeoplasmsMaleMiddle AgedAngiogenesis InhibitorsAntineoplastic AgentsBiomarkers, TumorIndazolespazopanibPyrimidinesSulfonamides

Identifiers

PMID29396560
PMCPMC5797076
OpenAlexW2807113487

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.