ArticleDevelopmental cell2018
A Lipid Transfer Protein Signaling Axis Exerts Dual Control of Cell-Cycle and Membrane Trafficking Systems.
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Article in Developmental cell, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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23citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
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Who cites it
23 citing papers in PubMed, 38 citations in OpenAlex.
- In vitro methods for measuring lipid binding, transfer and competitive displacement reactions by peripheral membrane proteins.Methods in enzymology · 2026Article
- A brief history of phosphatidylinositol transfer proteins: from the backwaters of cell biology to prime time in lipid signaling.Biochimica et biophysica acta. Molecular and cell biology of lipids · 2025Review
- Mammalian START-like phosphatidylinositol transfer proteins - Physiological perspectives and roles in cancer biology.Biochimica et biophysica acta. Molecular and cell biology of lipids · 2024Review
- Non-vesicular phosphatidylinositol transfer plays critical roles in defining organelle lipid composition.The EMBO journal · 2024Article
- Uncovering the Role of the Yeast Lysine Acetyltransferase NuA4 in the Regulation of Nuclear Shape and Lipid Metabolism.Molecular and cellular biology · 2024Article
- Roles of Phosphatidylinositol 4-Phosphorylation in Non-vesicular Cholesterol Trafficking.Advances in experimental medicine and biology · 2023Article
- Up-regulation of Osh6 boosts an anti-aging membrane trafficking pathway toward vacuoles.Microbial cell (Graz, Austria) · 2022Article
- Article
- New strategies for combating fungal infections: Inhibiting inositol lipid signaling by targeting Sec14 phosphatidylinositol transfer proteins.Advances in biological regulation · 2022Review
- Article
- Emerging Prospects for Combating Fungal Infections by Targeting Phosphatidylinositol Transfer Proteins.International journal of molecular sciences · 2021Review
- The Fast and the Furious: Golgi Contact Sites.Contact (Thousand Oaks (Ventura County, Calif.)) · 2021Article
- Phenomic screen identifies a role for the yeast lysine acetyltransferase NuA4 in the control of Bcy1 subcellular localization, glycogen biosynthesis, and mitochondrial morphology.PLoS genetics · 2020Article
- A Sec14-like phosphatidylinositol transfer protein paralog defines a novel class of heme-binding proteins.eLife · 2020Article
- Noncanonical regulation of phosphatidylserine metabolism by a Sec14-like protein and a lipid kinase.The Journal of cell biology · 2020Article
- Implications of Long Non-Coding RNAs in Age-Altered Proteostasis.Aging and disease · 2020Review
- Abundances of transcripts, proteins, and metabolites in the cell cycle of budding yeast reveal coordinate control of lipid metabolism.Molecular biology of the cell · 2020Article
- Genetic interaction profiles of regulatory kinases differ between environmental conditions and cellular states.Molecular systems biology · 2020Article
- Functional diversification of the chemical landscapes of yeast Sec14-like phosphatidylinositol transfer protein lipid-binding cavities.The Journal of biological chemistry · 2019Article
- An equal opportunity collaboration between lipid metabolism and proteins in the control of membrane trafficking in the trans-Golgi and endosomal systems.Current opinion in cell biology · 2019Review
Corrections and comments
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Authors and funding
14 authors at 7 institutions in 5 countries.
Jin HuangDepartment of Molecular and Cellular Medicine, Texas A&M Health Sciences Center, College Station, TX 77843-1114, USA.
Carl J MousleySchool of Biomedical Sciences, Curtin Health Innovation Research Institute (CHIRI), Faculty of Health Sciences, Curtin University, Bentley, WA 6102, Australia. Electronic address: carl.mousley@curtin.edu.au.
Louis DacquayOttawa Institute of Systems Biology, Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, ON, Canada.
Nairita MaitraDepartment of Biochemistry & Biophysics, Texas A&M University, College Station, TX 77843-2128, USA.
Guillaume DrinUniversité Côte d'Azur, CNRS, Institut de Pharmacologie Moléculaire et Cellulaire, Valbonne, France.
Chong HeBuck Institute for Research on Aging, 8001 Redwood Boulevard, Novato, CA 94945, USA.
Neale D RidgwayDepartments of Pediatrics and Biochemistry and Molecular Biology, Atlantic Research Centre, Dalhousie University, Halifax, NS B3H 4R2, Canada.
Ashutosh TripathiDepartment of Molecular and Cellular Medicine, Texas A&M Health Sciences Center, College Station, TX 77843-1114, USA.
Michael KennedyOttawa Institute of Systems Biology, Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, ON, Canada.
Brian K KennedyBuck Institute for Research on Aging, 8001 Redwood Boulevard, Novato, CA 94945, USA; Centre for Healthy Ageing, National University Health System and Departments of Biochemistry and Physiology, National University, Singapore, Singapore.
Wenshe LiuDepartment of Chemistry, Texas A&M University, College Station, TX 77843, USA.
Kristin BaetzOttawa Institute of Systems Biology, Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, ON, Canada.
Michael PolymenisDepartment of Biochemistry & Biophysics, Texas A&M University, College Station, TX 77843-2128, USA.
Vytas A BankaitisDepartment of Molecular and Cellular Medicine, Texas A&M Health Sciences Center, College Station, TX 77843-1114, USA; Department of Biochemistry & Biophysics, Texas A&M University, College Station, TX 77843-2128, USA; Department of Chemistry, Texas A&M University, College Station, TX 77843, USA. Electronic address: vytas@tamhsc.edu.
Texas A&M Health Science Center · USTexas A&M University · USUniversity of Ottawa · CABuck Institute for Research on Aging · USCentre National de la Recherche Scientifique · FRCurtin University · AUDalhousie University · CA
Funding
Role of the Phospholipids in Golgi Secretory FunctionR01GM044530 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BANKAITIS, VYTAS A · 1991 to 2019
$5.6MSystem approaches to determine mechanisms underlying yeast replicative agingR01AG043080 · NIA · BUCK INSTITUTE FOR RESEARCH ON AGING · PI KENNEDY, BRIAN K · 2012 to 2016
$3.0MCoupling Of Protein Synthesis With Cell DivisionR01GM123139 · NIGMS · TEXAS A&M AGRILIFE RESEARCH · PI POLYMENIS, MICHAEL S · 2017 to 2024
$2.9MCIHR MOP-136809NIA NIH HHS R01 AG043080NIGMS NIH HHS R01 GM044530NIGMS NIH HHS R01 GM123139
Abstract
Kes1/Osh4 is a member of the conserved, but functionally enigmatic, oxysterol binding protein-related protein (ORP) superfamily that inhibits phosphatidylinositol transfer protein (Sec14)-dependent membrane trafficking through the trans-Golgi (TGN)/endosomal network. We now report that Kes1, and select other ORPs, execute cell-cycle control activities as functionally non-redundant inhibitors of the G
Indexed as
Biological TransportCell CycleCell MembraneCell MovementEndosomesGolgi ApparatusHistone AcetyltransferasesLipidsMembrane ProteinsOxysterol Binding ProteinsPhospholipid Transfer ProteinsReceptors, SteroidSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSignal TransductionHistone AcetyltransferasesKES1 protein, S cerevisiaeLipidsMembrane ProteinsNuA4 protein, S cerevisiaeOxysterol Binding ProteinsPhospholipid Transfer ProteinsReceptors, SteroidSaccharomyces cerevisiae ProteinsSEC14 protein, S cerevisiaeagingcell cyclelipid exchange proteinslipid signalinglysine acetyltransferaseORPsphosphoinositidesPITPs
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.