Evidence map›Paper›PMID 29395912›Full record

ArticleNeuron2018

Clptm1 Limits Forward Trafficking of GABA

Yuan Ge, Yunhee Kang, Robert M Cassidy, Kyung-Mee Moon, Renate Lewis, Rachel O L Wong, Leonard J Foster, Ann Marie Craig

Open access · bronzeAbstract read
In one paragraph

Article in Neuron, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 78 citations in OpenAlex.

  1. Article
  2. Article
  3. Restoration of Extrasynaptic/Synaptic GABANeuroscience bulletin · 2026
    Article
  4. Article
  5. Comprehensive characterization of the RNA editing landscape in the human aging brains with Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  6. Proteostasis regulation of GABABiomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2025
    Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Haploinsufficiency of GABAThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  12. Article
  13. Established and emerging GABAFrontiers in pharmacology · 2024
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Clptm1, a new target in suppressing epileptic seizure by regulating GABAThe Kaohsiung journal of medical sciences · 2023
    Article
  20. Shisa7-Dependent Regulation of GABAThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Yuan GeDjavad Mowafaghian Centre for Brain Health and Department of Psychiatry, University of British Columbia, Vancouver, BC V6T 2B5, Canada.
Yunhee KangDjavad Mowafaghian Centre for Brain Health and Department of Psychiatry, University of British Columbia, Vancouver, BC V6T 2B5, Canada.
Robert M CassidyDjavad Mowafaghian Centre for Brain Health and Department of Psychiatry, University of British Columbia, Vancouver, BC V6T 2B5, Canada.
Kyung-Mee MoonDepartment of Biochemistry and Molecular Biology and Michael Smith Laboratories, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.
Renate LewisDepartment of Anatomy and Neurobiology, Washington University, St. Louis, MO 63110, USA.
Rachel O L WongDepartment of Biological Structure, University of Washington, Seattle, WA 98195, USA.
Leonard J FosterDepartment of Biochemistry and Molecular Biology and Michael Smith Laboratories, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.
Ann Marie CraigDjavad Mowafaghian Centre for Brain Health and Department of Psychiatry, University of British Columbia, Vancouver, BC V6T 2B5, Canada. Electronic address: acraig@mail.ubc.ca.
University of British Columbia · CAUniversity of Washington · USWashington University in St. Louis · US

Funding

INTERCELLULAR COMMUNICATION IN RETINAL DEVELOPMENTR01EY010699 · NEI · WASHINGTON UNIVERSITY · PI WONG, RACHEL O · 1994 to 2024
$8.6M
CIHRNEI NIH HHS R01 EY010699
6 · The paper itself

Abstract

In contrast with numerous studies of glutamate receptor-associated proteins and their involvement in the modulation of excitatory synapses, much less is known about mechanisms controlling postsynaptic GABA

Indexed as

Inhibitory Postsynaptic PotentialsAnimalsChlorocebus aethiopsCOS CellsEndoplasmic ReticulumFemaleHEK293 CellsHippocampusHomeostasisHumansMaleMembrane ProteinsMice, Inbred C57BLMice, TransgenicNeuronsPrimary Cell CultureClptm1 protein, mouseMembrane ProteinsProtein SubunitsReceptors, GABA-AClptm1GABAA receptorGABAergic transmissionGABA receptor-associated proteinhomeostasisinhibitory synapsereceptor traffickingsynaptic scalingtonic inhibition

Identifiers

PMID29395912
PMCPMC5810584
OpenAlexW2784441275

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.