ReviewTrends in biochemical sciences2018
Mind the Organelle Gap - Peroxisome Contact Sites in Disease.
Review in Trends in biochemical sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed.
- A mitochondria-driven quality control mechanism for peroxisomal membrane proteins.Nature communications · 2026Article
- Plant plastids: from evolutionary origins to functional specialization and organelle interactions.Journal of experimental botany · 2025Review
- Key challenges and recommendations for defining organelle membrane contact sites.Nature reviews. Molecular cell biology · 2025Review
- Mitochondrial membrane synthesis, remodelling and cellular trafficking.Journal of inherited metabolic disease · 2025Review
- Peroxisomal Localization of a Truncated HMG-CoA Reductase under Low Cholesterol Conditions.Biomolecules · 2024Article
- Systematic analysis of membrane contact sites ineLife · 2022Article
- ER as master regulator of membrane trafficking and organelle function.The Journal of cell biology · 2022Review
- Systematic multi-level analysis of an organelle proteome reveals new peroxisomal functions.Molecular systems biology · 2022Article
- Article
- Cellular metabolism therapy.Journal of translational medicine · 2022Article
- Article
- Peroxisomes contribute to intracellular calcium dynamics in cardiomyocytes and non-excitable cells.Life science alliance · 2021Article
- The Fast and the Furious: Golgi Contact Sites.Contact (Thousand Oaks (Ventura County, Calif.)) · 2021Article
- Maintaining social contacts: The physiological relevance of organelle interactions.Biochimica et biophysica acta. Molecular cell research · 2020Review
- Insufficiency of ciliary cholesterol in hereditary Zellweger syndrome.The EMBO journal · 2020Article
- Peroxisomal targeting of a protein phosphatase type 2C via mitochondrial transit.Nature communications · 2020Article
- A molecular toolbox for interrogation of membrane contact sites.The Journal of physiology · 2020Review
- Peroxisomal fission is modulated by the mitochondrial Rho-GTPases, Miro1 and Miro2.EMBO reports · 2020Article
- Organelle interplay-peroxisome interactions in health and disease.Journal of inherited metabolic disease · 2020Review
- Peroxisomal Membrane Contact Sites in Mammalian Cells.Frontiers in cell and developmental biology · 2020Review
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
The eukaryotic cell is organized as a complex grid system where membrane-bound cellular compartments, organelles, must be localized to the right place at the right time. One way to facilitate correct organelle localization and organelle cooperation is through membrane contact sites, areas of close proximity between two organelles that are bridged by protein/lipid complexes. It is now clear that all organelles physically contact each other. The main focus of this review is contact sites of peroxisomes, central metabolic hubs whose defects lead to a variety of diseases. New peroxisome contacts, their tethering complexes and functions have been recently discovered. However, if and how peroxisome contacts contribute to the development of peroxisome-related diseases is still a mystery.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.