Evidence map›Paper›PMID 29395264›Full record

Observational studyHeart & lung : the journal of critical care

Effect of symptoms on physical performance in COPD.

Jungeun Lee, Huong Q Nguyen, Monica E Jarrett, Pamela H Mitchell, Kenneth C Pike, Vincent S Fan

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in Heart & lung : the journal of critical care. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 39 citations in OpenAlex.

  1. Pooled it
  2. The prevalence and related factors of fatigue in patients with COPD: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2021
    Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Jungeun LeeSchool of Nursing, University of Washington, Seattle, WA, USA. Electronic address: jelee@uri.edu.
Huong Q NguyenReseach & Evaluation, Kaiser Permanente Southern California, Pasadena, CA, USA.
Monica E JarrettSchool of Nursing, University of Washington, Seattle, WA, USA.
Pamela H MitchellSchool of Nursing, University of Washington, Seattle, WA, USA.
Kenneth C PikeSchool of Nursing, University of Washington, Seattle, WA, USA.
Vincent S FanVA Puget Sound Health Care Center, Seattle, WA, USA.
University of Washington · USKaiser Permanente · USVA Puget Sound Health Care System · US

Funding

Depression and functional outcomes in COPD: Impact of genetics and inflammationR01HL093146 · NHLBI · UNIVERSITY OF WASHINGTON · PI FAN, VINCENT S, NGUYEN, HUONG Q · 2010 to 2014
$1.9M
NHLBI NIH HHS R01 HL093146
6 · The paper itself

Abstract

backgroundChronic obstructive pulmonary disease (COPD) patients experience multiple symptoms including dyspnea, anxiety, depression, and fatigue, which are highly correlated with each other. Together, those symptoms may contribute to impaired physical performance.

objectivesThe purpose of this study was to examine interrelationships among dyspnea, anxiety, depressive symptoms, and fatigue as contributing factors to physical performance in COPD.

methodsThis study used baseline data of 282 COPD patients from a longitudinal observational study to explore the relationship between depression, inflammation, and functional status. Data analyses included confirmatory factor analyses and structural equation modeling.

resultsDyspnea, anxiety and depression had direct effects on fatigue, and both dyspnea and anxiety had direct effects on physical performance. Higher levels of dyspnea were significantly associated with impaired physical performance whereas higher levels of anxiety were significantly associated with enhanced physical performance.

conclusionDyspnea was the strongest predictor of impaired physical performance in patients with COPD.

Indexed as

Physical Functional PerformanceAgedAnxietyDepressionDyspneaFactor Analysis, StatisticalFatigueFemaleHumansInflammationLongitudinal StudiesMaleMiddle AgedProspective StudiesPulmonary Disease, Chronic ObstructiveCOPDDyspneaFatiguePhysical performancePsychological symptoms

Identifiers

PMID29395264
PMCPMC5857230
OpenAlexW2793572583

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.