Evidence map›Paper›PMID 29395071›Full record

ArticleMolecular cell2018

Defining the Essential Function of Yeast Hsf1 Reveals a Compact Transcriptional Program for Maintaining Eukaryotic Proteostasis.

Eric J Solís, Jai P Pandey, Xu Zheng, Dexter X Jin, Piyush B Gupta, Edoardo M Airoldi, David Pincus, Vladimir Denic

Open access · bronzeAbstract readPublished Erratum
In one paragraph

Article in Molecular cell, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
8.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 147 citations in OpenAlex.

  1. More than the 'master regulator of cytosolic proteostasis': new roles for HSF1 in promoting tissue health.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Eric J Solís
Jai P Pandey
Xu Zheng
Dexter X Jin
Piyush B Gupta
Edoardo M Airoldi
David Pincus
Vladimir Denic
Whitehead Institute for Biomedical Research · USHarvard University · US

Funding

Mechanistic dissection of eukaryotic protein biogenesis and degradation pathwaysR35GM127136 · NIGMS · HARVARD UNIVERSITY · PI Vladimir Denic · 2018 to 2026
$5.0M
Quantitative approaches to reveal the homeostatic control mechanisms of stress reDP5OD017941 · OD · WHITEHEAD INSTITUTE FOR BIOMEDICAL RES · PI PINCUS, DAVID · 2013 to 2017
$2.4M
Defining the Essential Function of Heat Shock Factor and the Consequences of its Age-Associated DeclineR21AG050134 · NIA · HARVARD UNIVERSITY · PI DENIC, VLADIMIR · 2015 to 2016
$465k
NIA NIH HHS R21 AG050134NIGMS NIH HHS R35 GM127136NIH HHS DP5 OD017941
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID29395071
PMCPMC5813686
OpenAlexW2420903908

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.