Evidence map›Paper›PMID 29395057›Full record

ArticleCell stem cell2018

Jak1 Integrates Cytokine Sensing to Regulate Hematopoietic Stem Cell Function and Stress Hematopoiesis.

Maria Kleppe, Matthew H Spitzer, Sheng Li, Corinne E Hill, Lauren Dong, Efthymia Papalexi, Sofie De Groote, Robert L Bowman, Matthew Keller, Priya Koppikar and 6 more

Abstract readPublished Erratum
In one paragraph

Article in Cell stem cell, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Cancer discovery · 2019
    Article
  5. Article
  6. Loss of JAK1 Drives Innate Immune Deficiency.Frontiers in immunology · 2018
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors.

Maria Kleppe
Matthew H Spitzer
Sheng Li
Corinne E Hill
Lauren Dong
Efthymia Papalexi
Sofie De Groote
Robert L Bowman
Matthew Keller
Priya Koppikar
Franck T Rapaport
Julie Teruya-Feldstein
Jorge Gandara
Christopher E Mason
Garry P Nolan
Ross L Levine

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Synergistic role of signaling and epigenetics in leukemic transformationR35CA197594 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI Ross L Levine · 2017 to 2026
$11.4M
Role of TET2 mutations in malignant transformation and acute myeloid leukemiaR01CA173636 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI AIFANTIS, IANNIS, LEVINE, ROSS L · 2013 to 2022
$6.3M
NCI NIH HHS P30 CA008748NCI NIH HHS R01 CA173636NCI NIH HHS R35 CA197594
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID29395057
PMCPMC6260818

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.