Trial reportHealth and quality of life outcomes2018
Factors influencing health-related quality of life in patients with Type 1 diabetes.
Trial report in Health and quality of life outcomes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
15 citing papers in PubMed.
- Agreement and measurement properties of the interviewer-administered, self-completed and proxy-reported versions of the Tigrinya EQ-5D-Y-5L in Ethiopia.The European journal of health economics : HEPAC : health economics in prevention and care · 2026Article
- Quality of Life and Humanistic Burden of Adults with Type 1 Diabetes with Recurrent Severe Hypoglycemic Events and Impaired Awareness of Hypoglycemia Using a Continuous Glucose Monitor.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2026Article
- Economic Evaluation of the Metabolic and Bariatric Surgery Initiative for Patients With Obesity and Comorbid Diabetes in Queensland.Obesity science & practice · 2026Article
- Stress and Health-Related Quality of Life in Adults With Type 1 Diabetes: The Mediating Role of Perceived Support and Treatment Adherence.Journal of clinical nursing · 2026Observational
- Concept analysis of diabetes-related quality of life.Health and quality of life outcomes · 2025Review
- Health-related quality of life in pregnant women with type 1 diabetes and associations with maternal and neonatal complications.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Article
- Comparing quality of life in traditional face-to-face visits with a hybrid approach of telemedicine with in-person follow-ups in recent users of advanced closed-loop systems: a randomized controlled clinical trial in patients with type 1 diabetes.Therapeutic advances in endocrinology and metabolism · 2024Article
- Sociodemographic and Clinical Determinants on Health-Related Quality of Life in Emerging Andalusian Adults with Type 1 Diabetes: A Cross-Sectional Study.Journal of clinical medicine · 2023Article
- Health-related quality of life of people with type 2 diabetes and its associated factors at a tertiary care clinic in Ningbo, China: A cross-sectional study.Endocrinology, diabetes & metabolism · 2022Article
- Health-related quality of life measures in incarcerated populations: protocol for a scoping review.BMJ open · 2022Article
- Socio-economic correlates of quality of life in single and married urban individuals: a Polish case study.Health and quality of life outcomes · 2022Article
- Health-related quality of life in T1DM patients after high-dose cholecalciferol supplementation: data from a pilot clinical trial.Diabetology & metabolic syndrome · 2022Article
- A Cross-Sectional Study of Quality of Life Among Brazilian Adults With Type 1 Diabetes Treated With Insulin Glargine: Findings and Implications.Clinical diabetes : a publication of the American Diabetes Association · 2022Article
- Nutritional Determinants of Quality of Life in a Mediterranean Cohort: The SUN Study.International journal of environmental research and public health · 2020Article
- The cognitive and psychological effects of living with type 1 diabetes: a narrative review.Diabetic medicine : a journal of the British Diabetic Association · 2020Review
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
aimsGeneric, preference-based measures of health-related quality of life (HRQoL) are a common input to the economic evaluation of new health technologies. As such, it is important to explore what characteristics of patients with Type 1 diabetes might impact scores on such measures.
methodsThis study utilizes baseline data from a cluster-randomized trial that recruited patients with Type 1 diabetes at six centers across Ireland. Health-related quality of life was assessed using the three-level EuroQol EQ-5D (EQ-5D) measure. Patients' responses to individual dimensions of the EQ-5D were explored. To see which patient factors influenced EQ-5D scores, multivariate regression analysis was conducted with EQ-5D scores as the outcome variable.
resultsData was available for 437 Type 1 diabetes patients. The median age of these patients was 40 (IQR: 31-49) years and 53.8% were female. Overall, patients reported a high HRQoL based on EQ-5D scores (0.87 (SD: 0.19). Fifty-four percent of patients reported a perfect HRQoL. For those that reported problems, the most common dimension was the anxiety/depression dimension of the EQ-5D (29.6%). In the multivariate regression analysis, self-reported mental illness (- 0.22 (95% CI: -0.34, - 0.10)) and being unemployed (- 0.07 (95% CI: -0.13, - 0.02)) were negatively associated with EQ-5D scores (p < 0.05). The influence of self-reported mental illness was persistent in sensitivity analyses.
conclusionsThe study results indicate that patients with Type 1 diabetes report a high HRQoL based on responses to the EQ-5D. However, there are a substantial number of Type 1 diabetes patients that report problems in the anxiety/depression dimension, which may provide avenues to improve patients' HRQoL.
trial registrationCurrent Controlled Trials ISRCTN79759174 .
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.