SynthesisBMC cancer2018
Screening for distress in patients with primary brain tumor using distress thermometer: a systematic review and meta-analysis.
Synthesis in BMC cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07628647 (Pilot Study of the Living Well With Brain Cancer Intervention), which is not on this map. Cited by 34 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Pilot Study of the Living Well With Brain Cancer Intervention
Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.
- A systematic review and meta-analysis of psychological burden in family caregivers of patients with brain tumors.Scientific reports · 2025Pooled it
- A randomized controlled trial of emotion regulation therapy for cancer caregivers: A mechanism-targeted approach to addressing caregiver distress.Contemporary clinical trials · 2022Trial
- European Association for Palliative Care White Paper on spiritual care for people with neuro-oncological and neurodegenerative conditions: Integrative framework for practice, education, and research.Palliative & supportive care · 2026Review
- Construction and internal assessment of an exploratory risk prediction model for psychological distress in brain tumor patients: a cross-sectional study.BMC cancer · 2026Article
- The protective role of HCWs communication for the distress of newly diagnosed people with leukemia and lymphoma.PEC innovation · 2025Article
- Symptom distress and treatment interest for cognitive decline in neuro-oncology.Neuro-oncology practice · 2025Article
- Character strength patterns, social support and psychological distress in adolescents and young adults with cancer: A multicenter cross-sectional study.Asia-Pacific journal of oncology nursing · 2024Article
- Increased Distress in Neurooncological Patients, a Monocentric Longitudinal Study: When to Screen Which Patient?Diseases (Basel, Switzerland) · 2024Article
- Symptom experience and symptom distress in patients with malignant brain tumor treated with proton therapy: A five-year follow-up study.Technical innovations & patient support in radiation oncology · 2024Article
- Psycho-oncological burden in patients with brain metastases undergoing neurological surgery.Frontiers in oncology · 2024Article
- Influence of neuropathological diagnosis on psychooncological distress in neurooncological patients - a retrospective cross-sectional analysis.Frontiers in oncology · 2024Article
- Brain tumor-related epilepsy: an overview on neuropsychological, behavioral, and quality of life issues and assessment methodology.Frontiers in neurology · 2024Review
- Identification of health-related quality of life profiles among long-term survivors of primary central nervous system tumors.Journal of neuro-oncology · 2023Article
- Patterns and predictors of anxiety and depression symptom trajectories in patients diagnosed with primary brain tumors.Journal of neuro-oncology · 2023Article
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- Feasibility of a virtual reality intervention targeting distress and anxiety symptoms in patients with primary brain tumors: Interim analysis of a phase 2 clinical trial.Research square · 2023Article
- Impact of COVID-19 Epidemic on Psycho-Oncological Distress in Neuro-Oncological Patients.Current oncology (Toronto, Ont.) · 2022Article
- Resilience in Lower Grade Glioma Patients.Cancers · 2022Article
- Aspects of Clinical Utility of the Distress Thermometer and Problem List after Burns.European burn journal · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundPatients with primary brain tumors are reported to have an elevated level of distress prevalence, due to the functional sequelae and the unfavorable prognosis, but the estimated prevalence of this disorder varies among studies. The Distress Thermometer (DT) is widely used distress screening tools to identify patients suffering from elevated psychosocial distress. The objective of this meta-analysis is to get a summarized estimate of distress prevalence in adult primary brain tumor patients screened by the DT instrument to identify distress in brain tumor patients.
methodWe searched studies published in PubMed, PsycINFO, and Cochrane library through August 2017 and checked related reviews and meta-analyses for eligible studies. Studies were eligible if they were published in the peer-reviewed literature and evaluated distress level by Distress Thermometer. The prevalence of distress symptoms in patients with the intracranial tumor was estimated by study-level characteristics using stratified meta-analysis. The prevalence of distress level or symptoms during the follow-up examination at different time points was detected by secondary analysis of the longitudinal studies included.
resultsTwelve studies including a total of 2145 brain tumor patients were included in this analysis. Eight used a cross-sectional design and four were longitudinal. The pooled prevalence of distress was 38.2% (95% confidence interval (CI) 28.7%-47.7%) for the overall sample. The pooled prevalence of distress DT ≥4 was 41.1% (642/1686, 95% CI 28.6%-53.5%) and the pooled prevalence of distress by DT ≥6 was 29.7% (137/459, 95% CI 19.5%-39.9%). The distress symptom did not decrease in follow-up studies (Relative Increase Ratio:1.02, 95% CI, (0.78, 1.35)). A huge heterogeneity in different studies was detected, and different screening scales were not compared.
conclusionThe high prevalence of distress becomes an enormous challenge for primary brain tumor patients. Routine screening and evaluation of distress in brain tumor patients may assist medical workers to develop proper interventions, which may lead to better quality of life and oncology management.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.