Evidence map›Paper›PMID 29394510›Full record

ArticleDepression and anxiety2018

A longitudinal study of women's depression symptom profiles during and after the postpartum phase.

Molly Fox, Curt A Sandman, Elysia Poggi Davis, Laura M Glynn

Abstract read
In one paragraph

Article in Depression and anxiety, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  4. Trial
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  8. Review
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  11. Review
  12. Peripartum Depression: What's New?Current psychiatry reports · 2025
    Review
  13. Article
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  15. Article
  16. Article
  17. Article
  18. Observational
  19. Review
  20. The maternal reward system in postpartum depression.Archives of women's mental health · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Molly FoxDepartments of Anthropology, University of California, Los Angeles, CA, USA.ORCID 0000-0001-9219-8971
Curt A SandmanDepartment of Psychiatry & Human Behavior, University of California, Irvine, CA, USA.
Elysia Poggi DavisDepartment of Psychology, University of Denver, Denver, CO, USA.
Laura M GlynnDepartment of Psychology, Chapman University, Orange, CA, USA.

Funding

University of California Health Participation in the National COVID Cohort Collaborative (N3C)UL1TR001414 · NCATS · UNIVERSITY OF CALIFORNIA-IRVINE · PI COOPER, DAN M, VILAIN, ERIC J. · 2015 to 2023
$35.1M
Structural & Network-Function Correlates of Fragmented Early-Life Across SpeciesP50MH096889 · NIMH · UNIVERSITY OF CALIFORNIA-IRVINE · PI BARAM, TALLIE Z. · 2013 to 2023
$25.4M
Maternal Stress and Fetal/Infant DevelopmentR01NS041298 · NINDS · UNIVERSITY OF CALIFORNIA-IRVINE · PI SANDMAN, CURT ALAN · 2002 to 2006
$2.8M
Pregnancy Influences Environmental SensitivityR01HD040967 · NICHD · UNIVERSITY OF CALIFORNIA IRVINE · PI GLYNN, LAURA M · 2001 to 2005
$1.7M
Effects of Acculturation on Gestational Biology in Mexican-American Pregnant WomenK01DK105110 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI FOX, MOLLY MAURER · 2015 to 2021
$782k
NCATS NIH HHS UL1 TR001414NICHD NIH HHS R01 HD040967NIDDK NIH HHS K01 DK105110NIMH NIH HHS P50 MH096889NINDS NIH HHS R01 NS041298
6 · The paper itself

Abstract

backgroundAn issue of critical importance for psychiatry and women's health is whether postpartum depression (PPD) represents a unique condition. The Diagnostic and Statistical Manual of Mental Disorders asserts that major depressive disorder (MDD) may present with peripartum onset, without suggesting any other differences between MDD and PPD. The absence of any distinct features calls into question the nosologic validity of PPD as a diagnostic category. The present study investigates whether symptom profiles differ between PPD and depression occurring outside the postpartum phase.

methodsIn a prospective, longitudinal study of parturient women (N = 239), we examine the manifestation of depression symptoms. We assess factor structure of symptom profiles, and whether factors are differentially pronounced during and after the postpartum period.

resultsFactors were revealed representing: Worry, Emotional/Circadian/Energetic Dysregulation, Somatic/Cognitive, Appetite, Distress Display, and Anger symptoms. The factor structure was validated at postpartum and after-postpartum timepoints. Interestingly, the Worry factor, comprising anxiety and guilt, was significantly more pronounced during the postpartum timepoint, and the Emotional/Circadian/Energetic Dysregulation factor, which contained sadness and anhedonia, was significantly less pronounced during the postpartum period.

conclusionsThese results suggest that PPD may be a unique syndrome, necessitating research, diagnosis, and treatment strategies distinct from those for MDD. Results indicate the possibility that Worry is an enhanced feature of PPD compared to depression outside the postpartum period, and the crucial role of sadness/anhedonia in MDD diagnosis may be less applicable to PPD diagnosis.

Indexed as

AdultDepression, PostpartumFemaleHumansLongitudinal StudiesMajor Depressive DisorderYoung AdultclassificationdiagnosisDiagnostic and Statistical Manual of Mental Disorderspostpartum depressionprospective studiespsychiatric diagnosisstatistical factor analysissymptom clusterwomen's health

Identifiers

PMID29394510
PMCPMC5889323

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.