Evidence map›Paper›PMID 29394236›Full record

ArticleRetina (Philadelphia, Pa.)2019

IDENTIFICATION OF FACTORS RELATED TO SUBFOVEAL DETACHMENT SECONDARY TO EPIRETINAL MEMBRANE.

Ilkay Kilic Muftuoglu, Tiezhu Lin, Eric Nudleman, Raouf Gaber, Dirk-Uwe Bartsch, William R Freeman

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Retina (Philadelphia, Pa.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ilkay Kilic MuftuogluDepartment of Ophthalmology, Jacobs Retina Center, Shiley Eye Institute, University of California San Diego, La Jolla, California.
Tiezhu LinDepartment of Ophthalmology, Jacobs Retina Center, Shiley Eye Institute, University of California San Diego, La Jolla, California.
Eric NudlemanDepartment of Ophthalmology, Shiley Eye Institute, University of California San Diego, California.
Raouf GaberDepartment of Ophthalmology, Jacobs Retina Center, Shiley Eye Institute, University of California San Diego, La Jolla, California.
Dirk-Uwe BartschDepartment of Ophthalmology, Jacobs Retina Center, Shiley Eye Institute, University of California San Diego, La Jolla, California.
William R FreemanDepartment of Ophthalmology, Jacobs Retina Center, Shiley Eye Institute, University of California San Diego, La Jolla, California.
University of California, San Diego · US

Funding

Vision BiostatisticsP30EY022589 · NEI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Derek Stuart Welsbie · 2012 to 2026
$10.3M
TREATMENT OF RETINOPATHY ASSOCIATED WITH AIDSR01EY007366 · NEI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FREEMAN, WILLIAM R. · 1988 to 2013
$7.6M
Crystalline Antiproliferative Drugs for Intraocular DiseasesR01EY018589 · NEI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FREEMAN, WILLIAM R. · 2008 to 2011
$2.0M
SCH: Multimodal Retina Image Alignment and ApplicationsR01EY033847 · NEI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI AN, CHEOLHONG, BARTSCH, DIRK-UWE G · 2021 to 2024
$1.2M
Role of PDLIM1 in Retinal Vascular Leakage and ProliferationK08EY028999 · NEI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI NUDLEMAN, ERIC D · 2018 to 2020
$713k
NEI NIH HHS K08 EY028999NEI NIH HHS P30 EY022589NEI NIH HHS R01 EY007366NEI NIH HHS R01 EY018589NEI NIH HHS R01 EY033847
6 · The paper itself

Abstract

purposeTo demonstrate factors related to the presence of subfoveal detachment (SD) secondary to epiretinal membrane (ERM) and to characterize the predictors for the resolution of SD after membrane peeling.

methodsA retrospective chart review was conducted for the patients who underwent pars plana vitrectomy for the idiopathic ERM peeling. Preoperative spectral domain optical coherence tomography characteristics of the eyes including central foveal thickness, foveal center point thickness, presence of intraretinal cyst, continuity of the membrane, area of the membrane within fovea (1 mm), and entire macula (6 mm) were evaluated to find the best predictors for the presence of SD. These predictors as well as perioperative parameters including use of internal tamponade and volume of SD were considered for time of resolution of SD.

resultsOf 158 included eyes, 20.2% eyes (32 eyes) had SD, and the presence of SD was significantly related to involvement of the membrane within the macula. After surgery, SD completely resolved in 90.6% of eyes (29 eyes) at a median of 2.97 months (range: 0.03-12.0 months). The area of the membrane within fovea was the only significant predictor for time to resolution of SD (hazard ratio = 1.20, 95% confidence interval = 1.100-1.324, P = 0.021). A small percent of eyes showed some further changes including fluctuation (6.2%) or persistence (3.1%) of fluid.

conclusionA larger extension of ERM over the macula is related to higher likelihood of the presence of SD. Time for resolution of subfoveal detachment does not seem to be affected by the preoperative and perioperative factors except the extent of membrane within 1,000 μm of the fovea.

Indexed as

Visual AcuityAgedAged, 80 and overEpiretinal MembraneFemaleFollow-Up StudiesFovea CentralisHumansMaleMiddle AgedRetinal DetachmentRetrospective StudiesRisk FactorsSeverity of Illness IndexTomography, Optical CoherenceVitrectomy

Identifiers

PMID29394236
PMCPMC13001795
OpenAlexW2791573387

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.