Evidence map›Paper›PMID 29393927›Full record

ArticleActa otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale2018

Unravelling the risk factors that underlie oral and oropharyngeal surgery in elderly.

G Molteni, S Valerini, M Alicandri-Ciufelli, A E Sprio, E Crosetti, G N Berta, L Presutti, G Succo

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Cooperation between ENT surgeon and dentist in head and neck oncology.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2021
    Article
  4. Trans-oral robotic surgery for the management of oropharyngeal carcinomas: a 9-year institutional experience.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2019
    Article
  5. Long-term disease-free survival in surgically-resected oral tongue cancer: a 10-year retrospective study.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

G MolteniOtorhinolaryngology Service, AOUI Verona Hospital, University of Verona, Department of Head and Neck Surgery, Verona, Italy.
S ValeriniOtorhinolaryngology Service, AOUI Verona Hospital, University of Verona, Department of Head and Neck Surgery, Verona, Italy.
M Alicandri-CiufelliOtorhinolaryngology Service, AOUI Verona Hospital, University of Verona, Department of Head and Neck Surgery, Verona, Italy.
A E SprioDepartment of Clinical and Biological Sciences, University of Turin, Italy.
E CrosettiHead and Neck Oncology Service, Oncology Department, University of Turin, IRCCS FPO Candiolo Cancer Institute, Italy.
G N BertaDepartment of Clinical and Biological Sciences, University of Turin, Italy.
L PresuttiOtorhinolaryngology Service, AOUI Verona Hospital, University of Verona, Department of Head and Neck Surgery, Verona, Italy.
G SuccoHead and Neck Oncology Service, Oncology Department, University of Turin, IRCCS FPO Candiolo Cancer Institute, Italy.
University of Verona · ITCandiolo Cancer Institute · ITUniversity of Turin · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral squamous cell carcinoma (OSCC) diagnoses in elderly patients are expected to double in the next 20 years. Current guidelines suggest surgery as a preferred approach, but elderly patients are hardly considered suitable to challenging surgical treatments. Using a multi-centric retrospective analysis, we evaluated the outcomes of 99 patients affected by OSCC and aged at least 70, who underwent to either transoral procedures (TP), open neck resection without (OR) or with reconstruction (ORR). In our cohort, overall survival was significantly hampered by concomitant diseases and postsurgical complications, whose development is driven by the former. Thus, our findings support the growing acceptance that chronological age alone should not be a sufficient contraindication for aggressive surgery in the treatment of OSCC. However, elderly patients affected by OSCC are undoubtedly delicate surgical candidates and accurate selection prior to surgery with curative intent is mandatory.

Indexed as

AgedAged, 80 and overAge FactorsCarcinoma, Squamous CellFemaleHumansMaleOral Surgical ProceduresOropharyngeal NeoplasmsOtorhinolaryngologic Surgical ProceduresPlastic Surgery ProceduresPostoperative ComplicationsRetrospective StudiesRisk AssessmentRisk FactorsTreatment OutcomeComplicationsElderlyFree flapOral cancerQuality of lifeReconstructive surgery

Identifiers

PMID29393927
PMCPMC6265672
OpenAlexW2788452347

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.