Evidence map›Paper›PMID 29393901›Full record

ArticleBioengineering (Basel, Switzerland)2018

Effects of Heterologous tRNA Modifications on the Production of Proteins Containing Noncanonical Amino Acids.

Ana Crnković, Oscar Vargas-Rodriguez, Anna Merkuryev, Dieter Söll

Open access · goldAbstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Upgrading aminoacyl-tRNA synthetases for genetic code expansion.Current opinion in chemical biology · 2018
    Review
  11. Novel Biocomposite Engineering and Bio-Applications.Bioengineering (Basel, Switzerland) · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ana CrnkovićDepartment of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA. ana.crnkovic@yale.edu.ORCID 0000-0002-0581-1887
Oscar Vargas-RodriguezDepartment of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA. oscar.vargas@yale.edu.ORCID 0000-0002-2301-2800
Anna MerkuryevDepartment of Chemistry, Yale University, New Haven, CT 06520, USA. anna.merkuryev@yale.edu.
Dieter SöllDepartment of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520, USA. dieter.soll@yale.edu.ORCID 0000-0002-3077-8986
Yale University · US

Funding

Studies of Transfer RNAR35GM122560 · NIGMS · YALE UNIVERSITY · PI SOLL, DIETER · 2017 to 2022
$5.6M
NIGMS NIH HHS R35 GM122560
6 · The paper itself

Abstract

Synthesis of proteins with noncanonical amino acids (ncAAs) enables the creation of protein-based biomaterials with diverse new chemical properties that may be attractive for material science. Current methods for large-scale production of ncAA-containing proteins, frequently carried out in

Indexed as

aminoacyl-tRNA synthetasesgenetic code expansionnoncanonical amino acidsphosphoserineposttranscriptional modificationsprotein translationtRNA

Identifiers

PMID29393901
PMCPMC5874877
OpenAlexW2788763900

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.