Evidence map›Paper›PMID 29393378›Full record

ReviewInternational journal of oncology2018

Human papilloma virus: Apprehending the link with carcinogenesis and unveiling new research avenues (Review).

Daniel Boda, Anca Oana Docea, Daniela Calina, Mihaela Adriana Ilie, Constantin Caruntu, Sabina Zurac, Monica Neagu, Carolina Constantin, Daciana Elena Branisteanu, Vlad Voiculescu and 5 more

Open access · bronzeAbstract readReview
In one paragraph

Review in International journal of oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 105 papers.

0numbers the graph read from it
0cells of the map it votes in
105citing papers in PubMed
17.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

105 citing papers in PubMed, 177 citations in OpenAlex.

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45 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 2 countries.

Daniel BodaDermatology Research Laboratory, 'Carol Davila' University of Medicine and Pharmacy, 030167 Bucharest, Romania.
Anca Oana DoceaDepartment of Toxicology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Daniela CalinaDepartment of Clinical Pharmacy, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Mihaela Adriana IlieDermatology Research Laboratory, 'Carol Davila' University of Medicine and Pharmacy, 030167 Bucharest, Romania.
Constantin CaruntuDermatology Research Laboratory, 'Carol Davila' University of Medicine and Pharmacy, 030167 Bucharest, Romania.
Sabina ZuracDepartment of Pathology, 'Carol Davila' University of Medicine and Pharmacy, 030167 Bucharest, Romania.
Monica Neagu'Victor Babes' National Institute of Pathology, 050096 Bucharest, Romania.
Carolina Constantin'Victor Babes' National Institute of Pathology, 050096 Bucharest, Romania.
Daciana Elena BranisteanuDepartment of Dermatology, 'Gr. T. Popa' University of Medicine and Pharmacy, 700115 Iasi, Romania.
Vlad VoiculescuDepartment of Dermatology and Allergology, Elias Emergency University Hospital, 011461 Bucharest, Romania.
Charalampos MamoulakisDepartment of Urology, University General Hospital of Heraklion, University of Crete Medical School, 71003 Heraklion, Crete, Greece.
George TzanakakisLaboratory of Anatomy‑Histology‑Embryology, Medical School, University of Crete, 71003 Heraklion, Crete, Greece.
Demetrios A SpandidosLaboratory of Clinical Virology, Medical School, University of Crete, 71003 Heraklion, Crete, Greece.
Nikolaos DrakoulisResearch Group of Clinical Pharmacology and Pharmacogenomics, Faculty of Pharmacy, School of Health Sciences, National and Kapodistrian University of Athens, 15771 Athens, Greece.
Aristides M TsatsakisLaboratory of Toxicology, Medical School, University of Crete, 71003 Heraklion, Crete, Greece.
Carol Davila University of Medicine and Pharmacy · ROUniversity of Crete · GRInstitutul National Victor Babes · ROUniversity of Medicine and Pharmacy of Craiova · ROClinical Emergency Hospital Bucharest · ROGrigore T. Popa University of Medicine and Pharmacy · RONational and Kapodistrian University of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human papilloma viruses (HPV) are a small group of non‑enveloped viruses belonging to the Papillomaviridae family with strong similarities to polyoma viruses. The viral particles consist of a genome in the form of a circular double‑stranded DNA, encompassing eight open reading frames, as well as a non‑enveloped icosahedral capsid. HPV infection is considered the most common sexually transmitted disease in both sexes and is strongly implicated in the pathogenesis of different types of cancer. 'High‑risk' mucosal HPV types, predominantly types 16, 18, 31, 33 and 35, are associated with most cervical, penile, vulvar, vaginal, anal, oropharyngeal cancers and pre‑cancers. Screening for HPV is necessary for the prognosis and for determining treatment strategies for cancer. Novel HPV markers, including proteomic and genomic markers, as well as anti‑papillomavirus vaccines are currently available. The aim of this comprehensive review was to thoroughly present the updated information on virus development, cancer occurrence, treatment and prevention strategies, in an attempt to shed further light into the field, including novel research avenues.

Indexed as

CarcinogenesisBiomarkersEarly Detection of CancerEpitheliumFemaleHumansIncidenceMaleNeoplasmsPapillomaviridaePapillomavirus InfectionsPapillomavirus VaccinesProteomicsSex FactorsSexually Transmitted Diseases, ViralBiomarkersPapillomavirus Vaccines

Identifiers

PMID29393378
PMCPMC5807043
OpenAlexW2785453685

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.