Evidence map›Paper›PMID 29393045›Full record

ArticleeLife2018

Internal amino acid state modulates yeast taste neurons to support protein homeostasis in

Kathrin Steck, Samuel J Walker, Pavel M Itskov, Célia Baltazar, José-Maria Moreira, Carlos Ribeiro

Open access · goldAbstract read
In one paragraph

Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed
6.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 119 citations in OpenAlex.

  1. Article
  2. Ovary-Derived Signals Align Protein Appetite with Oogenesis.bioRxiv : the preprint server for biology · 2026
    Article
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  5. Article
  6. Article
  7. Finding a path: local search behavior of Drosophila larvae.The Journal of experimental biology · 2025
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Cell cycle re-entry in the agingbioRxiv : the preprint server for biology · 2024
    Article
  15. Article
  16. Article
  17. Article
  18. IR76b-expressing neurons inBiology letters · 2024
    Article
  19. Review
  20. Article

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Kathrin Steck *Champalimaud Centre for the Unknown, Lisbon, Portugal.ORCID http://orcid.org/0000-0003-2711-2873
Samuel J Walker *Champalimaud Centre for the Unknown, Lisbon, Portugal.ORCID http://orcid.org/0000-0003-3118-8467
Pavel M ItskovChampalimaud Centre for the Unknown, Lisbon, Portugal.
Célia BaltazarChampalimaud Centre for the Unknown, Lisbon, Portugal.
José-Maria MoreiraChampalimaud Centre for the Unknown, Lisbon, Portugal.
Carlos RibeiroChampalimaud Centre for the Unknown, Lisbon, Portugal.ORCID http://orcid.org/0000-0002-9542-7335
Champalimaud Foundation · PT

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI KEVIN R COOK · 2014 to 2026
$13.5M
Marie Curie FLiACT ITNNIH HHS P40 OD018537
6 · The paper itself

Abstract

To optimize fitness, animals must dynamically match food choices to their current needs. For drosophilids, yeast fulfills most dietary protein and micronutrient requirements. While several yeast metabolites activate known gustatory receptor neurons (GRNs) in

Indexed as

Feeding BehaviorProteostasisAmino AcidsAnimalsDrosophila melanogasterDrosophila ProteinsReceptors, Cell SurfaceYeastsAmino AcidsDrosophila Proteinsgustatory receptor, DrosophilaReceptors, Cell SurfaceBehaviorcalcium imagingD. melanogasterFeedingMetabolismneurosciencenutritionTaste

Identifiers

PMID29393045
PMCPMC5812714
OpenAlexW2755406805

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.