ReviewJournal of cachexia, sarcopenia and muscle2018
Determinants of muscle preservation in individuals with cerebral palsy across the lifespan: a narrative review of the literature.
Review in Journal of cachexia, sarcopenia and muscle, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
54 citing papers in PubMed, 113 citations in OpenAlex.
- RaceRunning training improves stamina and promotes skeletal muscle hypertrophy in young individuals with cerebral palsy.BMC musculoskeletal disorders · 2020Trial
- Physiological determinants of endurance capacity in individuals with cerebral palsy: a narrative review.Journal of rehabilitation medicine · 2026Review
- Kaempferol: advances in biosynthesis, molecular mechanisms, and therapeutic applications.Naunyn-Schmiedeberg's archives of pharmacology · 2026Review
- Changes in body composition and safety of exercise for individuals with severe cerebral palsy: single-group pre-post observational study.Journal of physical therapy science · 2026Article
- Morphological and Biochemical Abnormalities of Gracilis Muscle from Children with Cerebral Palsy.Journal of functional morphology and kinesiology · 2026Article
- Blood flow restriction during walking training in bilateral cerebral palsy (EMBRIN): a pilot feasibility study protocol.BMJ open · 2026Article
- The Reliability of Measuring Muscle Cross-Sectional Area in Children Undergoing Treatment for Musculoskeletal Sarcoma.Journal of cachexia, sarcopenia and muscle · 2026Article
- Protein Intake in Children with Cerebral Palsy: A Narrative Review Highlighting the Implications of Protein Intake on Muscle Mass, Growth, and Overall Nutritional Status.Neurosciences (Riyadh, Saudi Arabia) · 2026Review
- How Do Gait Outcomes Evolve in Adults with Spastic Cerebral Palsy Who Received Orthopedic Treatment in Childhood?Children (Basel, Switzerland) · 2026Article
- Outcomes of Pediatric Orthopedic Management of Ambulatory Cerebral Palsy Utilizing a Closely Monitored, Lifespan-Guided Approach.Children (Basel, Switzerland) · 2025Article
- Natural Flavonoids for the Prevention of Sarcopenia: Therapeutic Potential and Mechanisms.International journal of molecular sciences · 2025Review
- Serum metabolomics after exercise in ambulatory individuals with cerebral palsy.Developmental medicine and child neurology · 2025Article
- Limitations of the Washington Group Short Set in capturing moderate and severe mobility disabilities.Health affairs scholar · 2025Article
- Exploring the Relationship between Cerebral Palsy and Hip Dysplasia: Insights from the National Inpatient Sample.Medicina (Kaunas, Lithuania) · 2024Article
- Neuromuscular contributions to disability in children with cerebral palsy and the impact of dynamic stretching orthoses and therapeutic exercise interventions: a narrative review.Translational pediatrics · 2024Review
- Supported Standing and Supported Stepping Devices for Children with Non-Ambulant Cerebral Palsy: An Interdependence and F-Words Focus.International journal of environmental research and public health · 2024Article
- EFFECTIVENESS OF RADIAL EXTRACORPOREAL SHOCKWAVE THERAPY IN THE LOCAL MANAGEMENT OF HYPERTONIA (SPASTICITY AND DYSTONIA) IN PATIENTS WITH CEREBRAL PALSY.Journal of rehabilitation medicine. Clinical communications · 2024Article
- Article
- Lifelong Fitness in Ambulatory Children and Adolescents with Cerebral Palsy I: Key Ingredients for Bone and Muscle Health.Behavioral sciences (Basel, Switzerland) · 2023Article
- Ultrasound findings in painful spastic hip. Muscle thickness in children with cerebral palsy.BMC musculoskeletal disorders · 2023Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In individuals with cerebral palsy (CP), smaller muscle and atrophy are present at young age. Many people with CP also experience a decline in gross motor function as they age, which might be explained by the loss of muscle mass. The clinical observation of muscle wasting has prompted a comparison with sarcopenia in older adults, and the term accelerated musculoskeletal ageing is often used to describe the hallmark phenotype of CP through the lifespan. However, there has been very little research emphasis on the natural history of ageing with CP and even less with respect to the determinants or prevention of muscle loss with CP. Considering the burgeoning interest in the science of muscle preservation, this paper aims to (i) describe the characteristics of accelerated musculoskeletal ageing in people with CP, (ii) describe the pathophysiology of sarcopenia and parallels with CP, and (iii) discuss possible therapeutic approaches, based on established approaches for sarcopenia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.