Evidence map›Paper›PMID 29392887›Full record

ArticleJournal of cellular and molecular medicine2018

High-level expression of ARID1A predicts a favourable outcome in triple-negative breast cancer patients receiving paclitaxel-based chemotherapy.

Yuan-Feng Lin, Ing-Jy Tseng, Chih-Jung Kuo, Hui-Yu Lin, I-Jen Chiu, Hui-Wen Chiu

Open access · goldAbstract read
In one paragraph

Article in Journal of cellular and molecular medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Journal of Cancer · 2022
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  5. Article
  6. Review
  7. Article
  8. Article
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  11. FSH receptor binding inhibitor up-regulates ARID1A and PTEN genes associated with ovarian cancers in mice.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2019
    Article
  12. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Yuan-Feng LinGraduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Ing-Jy TsengSchool of Gerontology Healthy Management, College of Nursing, Taipei Medical University, Taipei, Taiwan.
Chih-Jung KuoDepartment of Veterinary Medicine, National Chung Hsing University, Taichung, Taiwan.
Hui-Yu LinGraduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
I-Jen ChiuGraduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Hui-Wen ChiuGraduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.ORCID 0000-0002-5027-390X
Taipei Medical University · TWTaipei Medical University-Shuang Ho Hospital · TWCardinal Tien Hospital · TWNational Chung Hsing University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Paclitaxel-based chemotherapy is a common strategy to treat patients with triple-negative breast cancer (TNBC). As paclitaxel resistance is still a clinical issue in treating TNBCs, identifying molecular markers for predicting pathologic responses to paclitaxel treatment is thus urgently needed. Here, we report that an AT-rich interaction domain 1A (ARID1A) transcript is up-regulated in paclitaxel-sensitive TNBC cells but down-regulated in paclitaxel-resistant cells upon paclitaxel treatment. Moreover, ARID1A expression was negatively correlated with the IC

Indexed as

AdultAgedAntineoplastic Combined Chemotherapy ProtocolsCell Line, TumorDisease-Free SurvivalDNA-Binding ProteinsDrug Resistance, NeoplasmFemaleGene Expression Regulation, NeoplasticHumansIndolesKaplan-Meier EstimateMiddle AgedNuclear Proteinsp38 Mitogen-Activated Protein KinasesPaclitaxelARID1A protein, humanDNA-Binding ProteinsIndolesNuclear Proteinsp38 Mitogen-Activated Protein KinasesPaclitaxelSCIO-469Transcription FactorsARID1Achemotherapyp38MAPKpaclitaxeltriple-negative breast cancer

Identifiers

PMID29392887
PMCPMC5867090
OpenAlexW2789994401

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.