Evidence map›Paper›PMID 29392632›Full record

ArticleTransgenic research2018

Arabidopsis glutamate:glyoxylate aminotransferase 1 (Ler) mutants generated by CRISPR/Cas9 and their characteristics.

Yaping Liang, Xiuying Zeng, Xinxiang Peng, Xuewen Hou

Abstract read
PubMed Publisher
In one paragraph

Article in Transgenic research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.7field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yaping LiangResearch Center of Plant Stress Biology, College of Life Sciences, South-China Agricultural University, Guangzhou, 510642, China.
Xiuying ZengResearch Center of Plant Stress Biology, College of Life Sciences, South-China Agricultural University, Guangzhou, 510642, China.
Xinxiang PengResearch Center of Plant Stress Biology, College of Life Sciences, South-China Agricultural University, Guangzhou, 510642, China.
Xuewen HouResearch Center of Plant Stress Biology, College of Life Sciences, South-China Agricultural University, Guangzhou, 510642, China. hxw1969@scau.edu.cn.ORCID 0000-0002-6448-5292
South China Agricultural University · CN

Funding

the Science and Technology Funding of Guangzhou 201707010032The Science and Technology Funding of Guangzhou 201607020006
6 · The paper itself

Abstract

Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated 9 (CRISPR/Cas9) technology provides an efficient tool for editing the genomes of plants, animals and microorganisms. Glutamate:glyoxylate aminotransferase 1 (GGAT1) is a key enzyme in the photorespiration pathway; however, its regulation mechanism is largely unknown. Given that EMS-mutagenized ggat1 (Col-0 background) M2 pools have been generated, ggat1 (Ler background) should be very useful in the positional cloning of suppressor and/or enhancer genes of GGAT1. Unfortunately, such ggat1 (Ler) mutants are not currently available. In this study, CRISPR/Cas9 was used to generate ggat1 (Ler) mutants. Two GGAT1 target single-guide RNAs (sgRNAs) were constructed into pYLCRISPR/Cas9P

Indexed as

CRISPR-Cas SystemsAgrobacteriumArabidopsisGene EditingMutationPhenotypePlants, Genetically ModifiedTransaminasesAt1g23310 protein, ArabidopsisTransaminasesArabidopsisCRISPR/Cas9Genome editing technologyGGAT1Photorespiration

Identifiers

PMID29392632
OpenAlexW2790865253

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.