ArticleJournal of materials science. Materials in medicine2018
Dry versus hydrated collagen scaffolds: are dry states representative of hydrated states?
Article in Journal of materials science. Materials in medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed.
- Controlled Magnesium Ion Delivery via Mg-Sputtered Nerve Conduit for Enhancing Peripheral Nerve Regeneration.Advanced healthcare materials · 2025Article
- Computed tomography technologies to measure key structural features of polymeric biomedical implants from bench to bedside.Journal of biomedical materials research. Part A · 2024Article
- Enhancing Guided Bone Regeneration with a Novel Carp Collagen Scaffold: Principles and Applications.Journal of functional biomaterials · 2024Review
- 3D-Printed Collagen-Nanocellulose Hybrid Bioscaffolds with Tailored Properties for Tissue Engineering Applications.ACS applied bio materials · 2023Article
- Thermoelectric Freeze-Casting of Biopolymer Blends: Fabrication and Characterization of Large-Size Scaffolds for Nerve Tissue Engineering Applications.Journal of functional biomaterials · 2023Article
- Aligned TiOPolymers · 2023Article
- Article
- Novel Hydrogel Material with Tailored Internal Architecture Modified by "Bio" Amphiphilic Components-Design and Analysis by a Physico-Chemical Approach.Gels (Basel, Switzerland) · 2022Article
- Computed Tomography as a Characterization Tool for Engineered Scaffolds with Biomedical Applications.Materials (Basel, Switzerland) · 2021Review
- Various Simulated Body Fluids Lead to Significant Differences in Collagen Tissue Engineering Scaffolds.Materials (Basel, Switzerland) · 2021Article
- Lumbar Interbody Fusion Conducted on a Porcine Model with a Bioresorbable Ceramic/Biopolymer Hybrid Implant Enriched with Hyperstable Fibroblast Growth Factor 2.Biomedicines · 2021Article
- Vancomycin-releasing cross-linked collagen sponges as wound dressings.Bosnian journal of basic medical sciences · 2021Article
- Review
- Microscopic Structure of Swollen Hydrogels by Scanning Electron and Light Microscopies: Artifacts and Reality.Polymers · 2020Article
- The Significance and Utilisation of Biomimetic and Bioinspired Strategies in the Field of Biomedical Material Engineering: The Case of Calcium Phosphat-Protein Template Constructs.Materials (Basel, Switzerland) · 2020Review
- Positive impact of dynamic seeding of mesenchymal stem cells on bone-like biodegradable scaffolds with increased content of calcium phosphate nanoparticles.Molecular biology reports · 2019Article
- Note on the use of different approaches to determine the pore sizes of tissue engineering scaffolds: what do we measure?Biomedical engineering online · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
Collagen composite scaffolds have been used for a number of studies in tissue engineering. The hydration of such highly porous and hydrophilic structures may influence mechanical behaviour and porosity due to swelling. The differences in physical properties following hydration would represent a significant limiting factor for the seeding, growth and differentiation of cells in vitro and the overall applicability of such hydrophilic materials in vivo. Scaffolds based on collagen matrix, poly(DL-lactide) nanofibers, calcium phosphate particles and sodium hyaluronate with 8 different material compositions were characterised in the dry and hydrated states using X-ray microcomputed tomography, compression tests, hydraulic permeability measurement, degradation tests and infrared spectrometry. Hydration, simulating the conditions of cell seeding and cultivation up to 48 h and 576 h, was found to exert a minor effect on the morphological parameters and permeability. Conversely, hydration had a major statistically significant effect on the mechanical behaviour of all the tested scaffolds. The elastic modulus and compressive strength of all the scaffolds decreased by ~95%. The quantitative results provided confirm the importance of analysing scaffolds in the hydrated rather than the dry state since the former more precisely simulates the real environment for which such materials are designed.
Indexed as
Identifiers
29392427What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.