Evidence map›Paper›PMID 29392419›Full record

ArticleAmino acids2018

Hepatic glutamate transport and glutamine synthesis capacities are decreased in finished vs. growing beef steers, concomitant with increased GTRAP3-18 content.

J Huang, Y Jia, Q Li, W R Burris, P J Bridges, J C Matthews

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Amino acids, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Metabolism and Nutrition of L-Glutamate and L-Glutamine in Ruminants.Animals : an open access journal from MDPI · 2024
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

J HuangDepartment of Animal and Food Sciences, University of Kentucky, Lexington, 40546, USA.
Y JiaDepartment of Animal and Food Sciences, University of Kentucky, Lexington, 40546, USA.
Q LiDepartment of Animal and Food Sciences, University of Kentucky, Lexington, 40546, USA.
W R BurrisDepartment of Animal and Food Sciences, University of Kentucky, Lexington, 40546, USA.
P J BridgesDepartment of Animal and Food Sciences, University of Kentucky, Lexington, 40546, USA.
J C MatthewsDepartment of Animal and Food Sciences, University of Kentucky, Lexington, 40546, USA. jmatthew@uky.edu.ORCID http://orcid.org/0000-0003-3219-9758
University of Kentucky · US

Funding

National Institute of Food and Agriculture 11303353
6 · The paper itself

Abstract

Hepatic glutamate uptake and conversion to glutamine is critical for whole-body N metabolism, but how this process is regulated during growth is poorly described. The hepatic glutamate uptake activities, protein content of system [Formula: see text] transporters (EAAC1, GLT-1) and regulatory proteins (GTRAP3-18, ARL6IP1), glutamine synthetase (GS) activity and content, and glutathione (GSH) content, were compared in liver tissue of weaned Angus steers randomly assigned (n = 8) to predominantly lean (growing) or predominantly lipid (finished) growth regimens. Steers were fed a cotton seed hull-based diet to achieve final body weights of 301 or 576 kg, respectively, at a constant rate of growth. Liver tissue was collected at slaughter and hepatic membranes fractionated. Total (75%), Na

Indexed as

AnimalsBiological Transport, ActiveCattleExcitatory Amino Acid Transporter 2Excitatory Amino Acid Transporter 3Glutamate-Ammonia LigaseGlutamic AcidGlutamineLiverMaleRed MeatExcitatory Amino Acid Transporter 2Excitatory Amino Acid Transporter 3Glutamate-Ammonia LigaseGlutamic AcidGlutamineCattleGlutamate transportGlutamine synthetaseGrowth phaseLiver

Identifiers

PMID29392419
PMCPMC5917004
OpenAlexW2791254576

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.