Evidence map›Paper›PMID 29392348›Full record

ArticlePediatric cardiology2018

Determinants of Increased Aortic Diameters in Young Normotensive Patients With Turner Syndrome Without Structural Heart Disease.

A Uçar, Melike Tuğrul, Bülent Oğuz Erol, Ensar Yekeler, Banu Aydın, Seher Yıldız, Kemal Nişli, Firdevs Baş, Şükran Poyrazoğlu, Feyza Darendeliler and 4 more

Abstract read
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In one paragraph

Article in Pediatric cardiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 2 countries.

A UçarDepartment of Pediatric Endocrinology and Diabetes, Faculty of Medicine, Istanbul University, Istanbul, Turkey. aucar76@yahoo.com.ORCID http://orcid.org/0000-0001-8144-8437
Melike TuğrulDepartment of Pediatric Endocrinology and Diabetes, Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Bülent Oğuz ErolDepartment of Pediatric Radiology, Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Ensar YekelerDepartment of Pediatric Radiology, Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Banu AydınDepartment of Pediatric Endocrinology and Diabetes, Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Seher YıldızDepartment of Pediatric Endocrinology and Diabetes, Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Kemal NişliDepartment of Pediatric Cardiology, Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Firdevs BaşDepartment of Pediatric Endocrinology and Diabetes, Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Şükran PoyrazoğluDepartment of Pediatric Endocrinology and Diabetes, Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Feyza DarendelilerDepartment of Pediatric Endocrinology and Diabetes, Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Nurçin SakaDepartment of Pediatric Endocrinology and Diabetes, Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Aylin Yetim ŞahinDepartment of Adolescent Medicine, Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Yasin YılmazDepartment of Pediatric Endocrinology and Diabetes, Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Rüveyde BundakDepartment of Pediatric Endocrinology and Diabetes, Faculty of Medicine, Istanbul University, Istanbul, Turkey.
Istanbul University · TRMemorial Sisli Hospital · TR

Funding

Bilimsel Araştirma Projeleri Birimi, Istanbul Üniversitesi 39521
6 · The paper itself

Abstract

Factors associated with aortic dilation and dissection in patients with Turner syndrome (TS) remain unclear. We assessed magnetic resonance imaging-based aortic diameters at nine predefined anatomic positions and examined associations of increased aortic diameters with B-type natriuretic peptide (BNP), A-type NP (ANP), growth hormone treatment, insulin-like growth factor 1 (IGF1), and estrogen status. Forty-seven patients with TS aged 7.3-21 years and 34 healthy peers were enrolled in this study. Aortic diameters were higher in patients with TS at three positions than in controls (p < 0.05). History of GH treatment, pubertal status, and serum estradiol levels were not associated with increased aortic diameters. Patients with TS had higher plasma BNP and ANP levels than controls. BNP and IGF1 were independently associated with the increase in aortic diameters in TS at three positions of the ascending aorta (R

Indexed as

AdolescentAdultAorta, ThoracicAortic DiseasesBlood PressureChildEstradiolFemaleHuman Growth HormoneHumansInsulin-Like Growth Factor IMagnetic Resonance ImagingNatriuretic PeptidesTurner SyndromeYoung AdultEstradiolHuman Growth HormoneIGF1 protein, humanInsulin-Like Growth Factor INatriuretic PeptidesAortic diametersB-natriuretic peptideInsulin-like growth factor 1Turner syndrome

Identifiers

PMID29392348
OpenAlexW2787371685

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.