Evidence map›Paper›PMID 29392245›Full record

ArticleDeep learning in medical image analysis and multimodal learning for clinical decision support : Third International Workshop, DLMIA 2017, and 7th International Workshop, ML-CDS 2017, held in conjunction with MICCAI 2017 Quebec City, QC,...2017

EMR-Radiological Phenotypes in Diseases of the Optic Nerve and their Association with Visual Function.

Shikha Chaganti, Jamie R Robinson, Camilo Bermudez, Thomas Lasko, Louise A Mawn, Bennett A Landman

Abstract read
In one paragraph

Article in Deep learning in medical image analysis and multimodal learning for clinical decision support : Third International Workshop, DLMIA 2017, and 7th International Workshop, ML-CDS 2017, held in conjunction with MICCAI 2017 Quebec City, QC,..., 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. AI in MRI: A case for grassroots deep learning.Magnetic resonance imaging · 2019
    Article
  3. Article
  4. Contextual Deep Regression Network for Volume Estimation in Orbital CT.Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shikha ChagantiDepartment of Computer Science, Vanderbilt University, Nashville, TN, USA 37235.
Jamie R RobinsonVanderbilt University Medical Center, 1211 Medical Center Dr, Nashville, TN 37232.
Camilo BermudezDepartment of Biomedical Engineering, Vanderbilt University, Nashville, TN, USA 37235.
Thomas LaskoDepartment of Biomedical Informatics, Vanderbilt University, Nashville, TN, USA 37235.
Louise A MawnVanderbilt Eye Institute, 2311 pierce Avenue, Nashville, TN, USA 37232.
Bennett A LandmanDepartment of Electrical Engineering, Vanderbilt University, Nashville, TN, USA 37235.

Funding

VANDERBILT UNIVERSITY CTSA FOR PEDIATRIC RESEARCHUL1RR024975 · NCRR · VANDERBILT UNIVERSITY · PI BERNARD, GORDON RAPHAEL · 2007 to 2011
$45.7M
The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
Vanderbilt Biomedical Informatics Training ProgramT15LM007450 · NLM · VANDERBILT UNIVERSITY · PI Jessica S. Ancker, Bradley A. Malin · 2002 to 2026
$19.7M
Quantitative Image Analysis Techniques for Optic Nerve DiseaseR21EY024036 · NEI · VANDERBILT UNIVERSITY · PI LANDMAN, BENNETT A. · 2014 to 2015
$410k
NCATS NIH HHS UL1 TR000445NCRR NIH HHS UL1 RR024975NEI NIH HHS R21 EY024036NLM NIH HHS T15 LM007450
6 · The paper itself

Abstract

Multi-modal analyses of diseases of the optic nerve, that combine radiological imaging with other electronic medical records (EMR), improve understanding of visual function. We conducted a study of 55 patients with glaucoma and 32 patients with thyroid eye disease (TED). We collected their visual assessments, orbital CT imaging, and EMR data. We developed an image-processing pipeline that segmented and extracted structural metrics from CT images. We derive EMR phenotype vectors with the help of PheWAS (from diagnostic codes) and ProWAS (from treatment codes). Next, we performed a principal component analysis and multiple-correspondence analysis to identify their association with visual function scores. We find that structural metrics derived from CT imaging are significantly associated with functional visual score for both glaucoma (R

Indexed as

CT imagingEMRMCAOptic nervePCARegression

Identifiers

PMID29392245
PMCPMC5790176

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.