Evidence map›Paper›PMID 29392158›Full record

ReviewJournal of medical imaging (Bellingham, Wash.)2018

Review of quantitative multiscale imaging of breast cancer.

Michael A Pinkert, Lonie R Salkowski, Patricia J Keely, Timothy J Hall, Walter F Block, Kevin W Eliceiri

Abstract readReview
In one paragraph

Review in Journal of medical imaging (Bellingham, Wash.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Harnessing non-destructive 3D pathology.Nature biomedical engineering · 2021
    Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Michael A PinkertMorgridge Institute for Research, Madison, Wisconsin, United States.ORCID https://orcid.org/0000-0002-3004-2282
Lonie R SalkowskiUniversity of Wisconsin-Madison, Department of Radiology, Madison, Wisconsin, United States.
Patricia J KeelyUniversity of Wisconsin-Madison, Department of Cell and Regenerative Biology, Madison, Wisconsin, United States.
Timothy J HallUniversity of Wisconsin-Madison, Department of Medical Physics, Madison, Wisconsin, United States.ORCID https://orcid.org/0000-0001-9850-6031
Walter F BlockUniversity of Wisconsin-Madison, Department of Medical Physics, Madison, Wisconsin, United States.
Kevin W EliceiriMorgridge Institute for Research, Madison, Wisconsin, United States.ORCID https://orcid.org/0000-0001-8678-670X

Funding

BIOTECHNOLOGY TRAINING PROGRAMT32GM008349 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI FOX, BRIAN G · 1989 to 2019
$22.5M
U.W. RADIOLOGICAL SCIENCES TRAINING PROGRAMT32CA009206 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Bryan Patrick Bednarz · 1985 to 2026
$12.1M
NCI NIH HHS T32 CA009206NIGMS NIH HHS T32 GM008349
6 · The paper itself

Abstract

Breast cancer is the most common cancer among women worldwide and ranks second in terms of overall cancer deaths. One of the difficulties associated with treating breast cancer is that it is a heterogeneous disease with variations in benign and pathologic tissue composition, which contributes to disease development, progression, and treatment response. Many of these phenotypes are uncharacterized and their presence is difficult to detect, in part due to the sparsity of methods to correlate information between the cellular microscale and the whole-breast macroscale. Quantitative multiscale imaging of the breast is an emerging field concerned with the development of imaging technology that can characterize anatomic, functional, and molecular information across different resolutions and fields of view. It involves a diverse collection of imaging modalities, which touch large sections of the breast imaging research community. Prospective studies have shown promising results, but there are several challenges, ranging from basic physics and engineering to data processing and quantification, that must be met to bring the field to maturity. This paper presents some of the challenges that investigators face, reviews currently used multiscale imaging methods for preclinical imaging, and discusses the potential of these methods for clinical breast imaging.

Indexed as

breast cancermultimodalmultiscalequantitative imaging

Identifiers

PMID29392158
PMCPMC5777512

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.