Evidence map›Paper›PMID 29392157›Full record

ArticleNeurophotonics2018

Prefrontal hemodynamic changes measured using near-infrared spectroscopy during the Valsalva maneuver in patients with orthostatic intolerance.

Yoo Hwan Kim, Zephaniah Phillips V, Seung-Ho Paik, Nam-Joon Jeon, Beop-Min Kim, Byung-Jo Kim

Open access · bronzeAbstract read
In one paragraph

Article in Neurophotonics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yoo Hwan KimHallym University Medical Center, Department of Neurology, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0002-0445-7185
Zephaniah Phillips VKorea University College of Health Science, Department of Bioconvergence Engineering, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0002-9532-5769
Seung-Ho PaikKorea University College of Health Science, Department of Bioconvergence Engineering, Seoul, Republic of Korea.
Nam-Joon JeonKorea University Anam Hospital, Neurophysiology Laboratory, Seoul, Republic of Korea.
Beop-Min KimKorea University College of Health Science, Department of Bioconvergence Engineering, Seoul, Republic of Korea.
Byung-Jo KimKorea University Medical Center, Department of Neurology, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0002-0445-7185
Hallym University Medical Center · KRKorea University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Valsalva maneuver (VM) with beat-to-beat blood pressure and heart rate monitoring are used to evaluate orthostatic intolerance (OI). However, they lack the ability to detect cerebral hemodynamic changes, which may be a cause of OI symptoms. Therefore, we utilized near-infrared spectroscopy during VM. Patients with OI symptoms and normal healthy subjects were recruited. Patients were subgrouped according to VM results: patients with normal VM (NVM) and abnormal VM (AbVM). Oxyhemoglobin (HbO), deoxyhemoglobin, and total hemoglobin changes were measured at four different source-detector distances (SD) (15, 30, 36, and 45 mm), and latency, amplitude, duration, and integrated total signal were calculated. Those parameters were compared between a normal healthy control (HC) group and the two OI patient subgroups. We found that HbO increment latency at 30-mm SD in the HC, NVM, and AbVM groups was as follows: [Formula: see text], [Formula: see text], and [Formula: see text], respectively ([Formula: see text]). Among the four parameters we evaluated, latency of HbO increment was the best marker for differentiating OI.

Indexed as

near-infraredorthostatic intolerancespectroscopyValsalva maneuver

Identifiers

PMID29392157
PMCPMC5786506
OpenAlexW2787185882

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.