Evidence map›Paper›PMID 29392143›Full record

ArticleJournal of immunology research2017

Antibodies against Pneumococcal Capsular Polysaccharides and Natural Anti-Galactosyl (Alpha-Gal) in Patients with Humoral Immunodeficiencies.

P Kralickova, J Kuhnova, O Soucek, P Vodarek, P Zak, M Simkovic, M Motyckova, L Smolej, E Mala, C Andrys and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of immunology research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Diagnostic Vaccination in Clinical Practice.Frontiers in immunology · 2021
    Article
  2. Serum From Melioidosis Survivors Diminished IntracellularFrontiers in cellular and infection microbiology · 2020
    Article
  3. Natural antibodies - facts known and unknown.Central-European journal of immunology · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

P KralickovaInstitute of Clinical Immunology and Allergology, Faculty of Medicine in Hradec Kralove, Charles University and University Hospital Hradec Kralove, Hradec Kralove, Czech Republic.ORCID 0000-0001-6402-3816
J KuhnovaDepartment of Mathematics, Faculty of Science, University of Hradec Kralove, Hradec Kralove, Czech Republic.ORCID 0000-0001-9223-5672
O SoucekInstitute of Clinical Immunology and Allergology, Faculty of Medicine in Hradec Kralove, Charles University and University Hospital Hradec Kralove, Hradec Kralove, Czech Republic.
P Vodarek4th Department of Internal Medicine-Haematology, Faculty of Medicine, Charles University and University Hospital Hradec Kralove, Hradec Kralove, Czech Republic.
P Zak4th Department of Internal Medicine-Haematology, Faculty of Medicine, Charles University and University Hospital Hradec Kralove, Hradec Kralove, Czech Republic.
M Simkovic4th Department of Internal Medicine-Haematology, Faculty of Medicine, Charles University and University Hospital Hradec Kralove, Hradec Kralove, Czech Republic.
M Motyckova4th Department of Internal Medicine-Haematology, Faculty of Medicine, Charles University and University Hospital Hradec Kralove, Hradec Kralove, Czech Republic.
L Smolej4th Department of Internal Medicine-Haematology, Faculty of Medicine, Charles University and University Hospital Hradec Kralove, Hradec Kralove, Czech Republic.
E MalaInstitute of Clinical Immunology and Allergology, Faculty of Medicine in Hradec Kralove, Charles University and University Hospital Hradec Kralove, Hradec Kralove, Czech Republic.
C AndrysInstitute of Clinical Immunology and Allergology, Faculty of Medicine in Hradec Kralove, Charles University and University Hospital Hradec Kralove, Hradec Kralove, Czech Republic.
J KrejsekInstitute of Clinical Immunology and Allergology, Faculty of Medicine in Hradec Kralove, Charles University and University Hospital Hradec Kralove, Hradec Kralove, Czech Republic.ORCID 0000-0003-2778-6800
V ThonDepartment of Clinical Immunology and Allergy, Faculty of Medicine, Masaryk University, St. Anne's University Hospital, Brno, Czech Republic.ORCID 0000-0001-9474-2133
Charles University · CZMasaryk University · CZUniversity of Hradec Králové · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Humoral deficiencies represent a broad group of disorders. The aim of the study was to compare the levels of antibodies against pneumococcal capsular polysaccharides (anti-PCP) and natural anti-galactosyl (anti-Gal) antibodies in (1) patients with chronic lymphocytic leukaemia (CLL), (2) patients with common variable immunodeficiency (CVID), and (3) a healthy population and to explore their diagnostic and prognostic potential. Serum immunoglobulin levels and levels of anti-Gal IgG, IgA, and IgM and anti-PCP IgG and IgG2 were determined in 59 CLL patients, 30 CVID patients, and 67 healthy controls. Levels of IgG, IgA, IgM, anti-Gal IgA, anti-Gal IgM, and anti-PCP IgA were lower in CLL and CVID patients than in healthy controls (

Indexed as

AdolescentAdultAgedAged, 80 and overAntibodies, BacterialAutoantibodiesBacterial CapsulesBiomarkersCommon Variable ImmunodeficiencyFemaleGalactosylceramidesHumansImmunity, HumoralImmunoglobulin AImmunoglobulin GImmunoglobulin MAntibodies, BacterialAutoantibodiesBiomarkersGalactosylceramidesImmunoglobulin AImmunoglobulin GImmunoglobulin M

Identifiers

PMID29392143
PMCPMC5748103
OpenAlexW2773888054

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.