Evidence map›Paper›PMID 29392090›Full record

ReviewAging and disease2018

Acute Sarcopenia Secondary to Hospitalisation - An Emerging Condition Affecting Older Adults.

Carly Welch, Zaki K Hassan-Smith, Carolyn A Greig, Janet M Lord, Thomas A Jackson

Registry-linked trialOpen access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Aging and disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03858192 (Understanding Acute Sarcopenia), which is not on this map. Cited by 115 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
115citing papers in PubMed, 10 pooled it
13.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03858192 naunknown statusnot on this mapstarted 2019, after this paper: background citation

Understanding Acute Sarcopenia: a Time-limited Cohort Study to Characterise Changes in Muscle Mass and Physical Function in Older Adults Following Hospitalisation

TypeinterventionalSponsorUniversity of BirminghamRan2019 to 2021Enrolled168ConditionsSarcopeniaArmsColorectal surgery procedure, Emergency abdominal surgery, Antibiotics
3 · Its place in the literature

Who cites it

115 citing papers in PubMed, 10 syntheses or guidelines pooled it, 215 citations in OpenAlex.

  1. Pooled it
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  4. ShortWorld journal of gastroenterology · 2023
    Pooled it
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  6. Exercise for acutely hospitalised older medical patients.The Cochrane database of systematic reviews · 2022
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55 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Carly Welch1Institute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
Zaki K Hassan-Smith2Queen Elizabeth Hospital Birmingham, Edgbaston, Birmingham: B15 2WB, UK.
Carolyn A Greig5School of Sport, Exercise & Rehabilitation Sciences, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
Janet M Lord1Institute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
Thomas A Jackson1Institute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.
University of Birmingham · GBQueen Elizabeth Hospital Birmingham · GB

Funding

Medical Research Council MR/K00414X/1Medical Research Council MR/P021220/1
6 · The paper itself

Abstract

There has been increasing interest and research into sarcopenia in community-dwelling older adults since the European Working Group on Sarcopenia in Older People (EWGSOP) agreed a consensus definition in 2010. Sarcopenia has been defined as loss of muscle mass with loss of muscle function (strength or physical performance), with measurements two Standard Deviations (SDs) below the mean of a young reference population. This definition does not necessitate longitudinal measurements, or the absence of acute illness and diagnosis can be made from single measurements. We hypothesise that hospitalisation, due to a combination of acute inflammatory burden and muscle disuse, leads to an acute decline in muscle mass and function and may lead to some individuals meeting criteria for sarcopenia, acutely, based on the EWGSOP definition. This may be partially recoverable or may lead to increased risk of developing sarcopenia long-term. We have denoted the term "acute sarcopenia" to refer to acute loss of muscle mass and function associated with hospitalisation. This review discusses some of the current available research in this context and also identifies some of the knowledge gaps and potential areas for future research.

Indexed as

acute illnessdisuse muscle atrophyhospitalisationmuscle wasting disorderssarcopenia

Identifiers

PMID29392090
PMCPMC5772853
OpenAlexW2785297623

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.