Evidence map›Paper›PMID 29392084›Full record

ArticleAging and disease2018

Cardiovascular Risk Factors Are Correlated with Low Cognitive Function among Older Adults Across Europe Based on The SHARE Database.

Joana Lourenco, Antonio Serrano, Alice Santos-Silva, Marcos Gomes, Claudia Afonso, Paula Freitas, Constanca Paul, Elisio Costa

Abstract read
In one paragraph

Article in Aging and disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Hearing loss and dementia: radiologic and biomolecular basis of their shared characteristics. A systematic review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021
    Pooled it
  2. Pooled it
  3. Article
  4. Hearing Loss and Alzheimer Disease.Current topics in behavioral neurosciences · 2025
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Increased Risk of Neurodegenerative Dementia after Benign Paroxysmal Positional Vertigo.International journal of environmental research and public health · 2021
    Article
  11. Observational
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Joana Lourenco1Family Health Unit of Pedras Rubras, Maia, Portugal.
Antonio Serrano1Family Health Unit of Pedras Rubras, Maia, Portugal.
Alice Santos-Silva4UCIBIO, REQUIMTE and Faculty of Pharmacy, University of Porto, Porto, Portugal.
Marcos Gomes4UCIBIO, REQUIMTE and Faculty of Pharmacy, University of Porto, Porto, Portugal.
Claudia Afonso2Faculty of Nutrition and Food Sciences, University of Porto, Porto, Portugal.
Paula Freitas5Department of Endocrinology, Diabetes and Metabolism, Centro Hospitalar São João, Porto, Portugal.
Constanca Paul3Center for Health Technology and Services Research (CINTESIS), Porto, Portugal.
Elisio Costa4UCIBIO, REQUIMTE and Faculty of Pharmacy, University of Porto, Porto, Portugal.

Funding

HRS Yrs29-34: Y33 SSA CoFundingU01AG009740 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Jessica Faul, KENNETH M LANGA · 1990 to 2026
$555.8M
Understanding and Improving Healthcare Decision-Making and Outcomes for People Living with Alzheimer's Disease and Related DementiasP01AG005842 · NIA · NATIONAL BUREAU OF ECONOMIC RESEARCH · PI KOSALI ILAYPERUMA SIMON · 1986 to 2026
$56.5M
WEALTH DISPARITIES AMONG MATURE AND OLDER ADULTSP01AG008291 · NIA · RAND CORPORATION · PI HURD, MICHAEL D · 1989 to 2018
$19.4M
RAND CENTER FOR THE STUDY OF AGINGP30AG012815 · NIA · RAND CORPORATION · PI HURD, MICHAEL D · 1999 to 2020
$13.7M
DEVELOPING AN ISRAELI VERSION OF THE HRS/SHARE PROJECTR21AG025169 · NIA · HEBREW UNIVERSITY OF JERUSALEM · PI LITWIN, HOWARD · 2004 to 2006
$297k
NIA NIH HHS P01 AG005842NIA NIH HHS P01 AG008291NIA NIH HHS P30 AG012815NIA NIH HHS R21 AG025169NIA NIH HHS U01 AG009740
6 · The paper itself

Abstract

Increased life expectancy is associated with a high prevalence of chronic, non-communicable diseases including cognitive decline and dementia. The purpose of this study was to evaluate the prevalence of cognitive impairment using three cognitive abilities (verbal fluency, numeracy and perceived memory) and their association with cardiovascular risk factors in seniors across Europe. Data from participants in wave 4 of the SHARE (Survey of Health, Ageing, and Retirement in Europe) database was used. Cognitive performance in perceived memory, verbal fluency and numeracy was evaluated using simple tests and a memory complaints questionnaire. Clinical and sociodemographic variables were also studied for potential associations. Standardised prevalence rates of cognitive impairment based on age and gender were calculated by country. The prevalence of cognitive impairment was 28.02% for perceived memory, 27.89% for verbal fluency and 20.75% for numeracy throughout the 16 evaluated countries. Years of education, being a current or former smoker, number of chronic diseases, diabetes or hyperglycemia, heart attack and stroke were all independent variables associated with impairment in the three studied cognitive abilities. We also found independent associations between physical inactivity and verbal fluency and numeracy impairment, as well as hypertension and perceived memory impairment. Lower performance in the evaluated cognitive abilities and higher memory complaints are highly prevalent, have a heterogeneous distribution across Europe, and are associated with multiple factors, most of which are potentially preventable or treatable, especially cardiovascular risk factors.

Indexed as

ageingcardiovascular risk factorschronic diseasescognitive function

Identifiers

PMID29392084
PMCPMC5772862

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.