Evidence map›Paper›PMID 29392078›Full record

ArticleAging and disease2018

PARP-1 Inhibition Rescues Short Lifespan in Hyperglycemic

Qianghua Xia, Sumei Lu, Julian Ostrovsky, Shana E McCormack, Marni J Falk, Struan F A Grant

Open access · goldAbstract read
In one paragraph

Article in Aging and disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Biochemical Targets and Molecular Mechanism of Matrine against Aging.International journal of molecular sciences · 2023
    Article
  7. Article
  8. NADNature reviews. Molecular cell biology · 2021
    Review
  9. NADNature metabolism · 2020
    Review
  10. TheDiabetes care · 2019
    Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Qianghua Xia *1Division of Human Genetics, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Sumei Lu *1Division of Human Genetics, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Julian Ostrovsky1Division of Human Genetics, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Shana E McCormack2Division of Endocrinology and Diabetes, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Marni J Falk1Division of Human Genetics, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Struan F A Grant1Division of Human Genetics, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Children's Hospital of Philadelphia · USUniversity of Pennsylvania · US

Funding

Career Development Program in Pediatric Diabetes Research (K12) at CHOPK12DK094723 · NIDDK · CHILDREN'S HOSP OF PHILADELPHIA · PI WILLI, STEVEN M · 2011 to 2020
$3.6M
Translational investigation of abnormal fat metabolism in mitochondrial diseaseK23DK102659 · NIDDK · CHILDREN'S HOSP OF PHILADELPHIA · PI MCCORMACK, SHANA ERIN · 2015 to 2017
$515k
NIDDK NIH HHS K12 DK094723NIDDK NIH HHS K23 DK102659
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

C. elegansGLP-1glucosePARP-1TCF7L2

Identifiers

PMID29392078
PMCPMC5772855
OpenAlexW2784776050

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.