ArticleVeterinary world2017
Ocular squamous cell carcinoma in Holstein cows from the South of Brazil.
Article in Veterinary world, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
9 citing papers in PubMed, 15 citations in OpenAlex.
- Bovine Ocular Squamous Cell Carcinoma-A Descriptive Epidemiological Survey in the Azores, Portugal.Veterinary sciences · 2026Article
- Ocular squamous cell carcinoma in cattle: clinicopathological and prognostic considerations.Brazilian journal of veterinary medicine · 2026Article
- Ocular and perineal squamous cell carcinomas in a Holstein Friesian cow.Open veterinary journal · 2024Article
- Relative and Quantitative Characterization of the Bovine Bacterial Ocular Surface Microbiome in the Context of Suspected Ocular Squamous Cell Carcinoma.Animals : an open access journal from MDPI · 2023Article
- Neoplasms in Domestic Ruminants and Swine: A Systematic Literature Review.Veterinary sciences · 2023Review
- An investigation of bovine papillomaviruses from ocular squamous cell carcinomas in cattle.Iranian journal of veterinary research · 2023Article
- Correlation between p53 and Mdm2 expression with histopathological parameters in cattle squamous cell carcinomas.Veterinary world · 2022Article
- Immunohistochemical Studies of Cytokeratins and Differentiation Markers in Bovine Ocular Squamous Cell Carcinoma.Veterinary sciences · 2020Article
- Identification of bovine papillomavirus type 1 and 2 from bovine anogenital fibropapillomas.The Journal of veterinary medical science · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimThe aim of this study was to investigate 10 cases of bovine ocular squamous cell carcinoma (OSCC) diagnosed in Holstein or Holstein-crosses cows. MATERIALS AND
methodsThe investigation was performed exclusively in OSCC cases diagnosed in the State of Paraná and Santa Catarina. A combination of two previously existing histopathological classifications systems was used. The tissue samples were tested for immunoexpression of p53 and p16 and polymerase chain reaction (PCR) for bovine herpesvirus and papillomavirus.
resultsA positive correlation between number of mitotic figures and tissue invasion was found. Anaplasia parameters did not correlate well with tumor invasion of deeper tissues and mitotic counts. Six of 10 OSCC cases were in animals with heavily pigmented eyes. Immunoexpression of p53 and p16 was observed in 3 cases each. Bovine herpesvirus and papillomavirus were not detected by PCR.
conclusionsOur results indicate that OSCC occurrence is most likely multifactorial with genetic, phenotypic, and environmental influences contributing to the pathogenesis of the disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.