Evidence map›Paper›PMID 29391593›Full record

ArticleEuropean journal of clinical nutrition2018

Vitamin D status and risk for sarcopenia in youth with inflammatory bowel diseases.

D R Mager, M W Carroll, E Wine, K Siminoski, K MacDonald, C L Kluthe, P Medvedev, M Chen, J Wu, J M Turner and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in European journal of clinical nutrition, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Body Composition in Inflammatory Bowel Disease.Archives of Iranian medicine · 2023
    Review
  11. Article
  12. Review
  13. Sarcopenia is highly prevalent in children with autoimmune liver diseases and is linked to visceral fat and parent-perceived general health.Liver international : official journal of the International Association for the Study of the Liver · 2022
    Article
  14. Review
  15. Review
  16. Review
  17. Sarcopenia in Children With End-Stage Liver Disease on the Transplant Waiting List.Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 2021
    Article
  18. Review
  19. Review
  20. Sarcopenia in Autoimmune and Rheumatic Diseases: A Comprehensive Review.International journal of molecular sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

D R MagerDepartment of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Alberta, Canada.
M W CarrollDepartment of Pediatrics, University of Alberta, Edmonton, Alberta, Canada.
E WineDepartment of Pediatrics, University of Alberta, Edmonton, Alberta, Canada.ORCID http://orcid.org/0000-0002-3458-4142
K SiminoskiDepartment of Radiology and Diagnostic Imaging, University of Alberta, Edmonton, Alberta, Canada.
K MacDonaldDepartment of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Alberta, Canada.
C L KlutheDepartment of Pediatrics, University of Alberta, Edmonton, Alberta, Canada.
P MedvedevDepartment of Pediatrics, University of Alberta, Edmonton, Alberta, Canada.
M ChenDivision of Pediatric Gastroenterology, Stollery Children's Hospital, Edmonton, Alberta, Canada.
J WuDivision of Pediatric Gastroenterology, Stollery Children's Hospital, Edmonton, Alberta, Canada.
J M TurnerDepartment of Pediatrics, University of Alberta, Edmonton, Alberta, Canada.
H Q HuynhDepartment of Pediatrics, University of Alberta, Edmonton, Alberta, Canada. mager@ualberta.ca.
University of Alberta · CAStollery Children's Hospital · CA

Funding

CIHR
6 · The paper itself

Abstract

Suboptimal vitamin D (vitD) status and reduced lean body mass are highly prevalent in pediatric inflammatory bowel diseases (IBD). The study objective was to determine sarcopenia prevalence and associations with vitD status in newly diagnosed pediatric IBD. Children with Crohn's disease (CD; n = 58) and ulcerative colitis (UC; n = 27) were included. Primary outcomes included body composition (total/regional/percent fat mass (FM), fat-free mass (FFM), skeletal muscle mass (SMM)), and vitD status (serum 25(OH)D). Sarcopenia was defined as SMM-z < -2. Additional variables measured included serum CRP, ESR, anthropometric, Pediatric Crohn's Disease Activity Index (PCDAI), and the Pediatric Ulcerative Colitis Disease Activity index (PUCAI). Sarcopenia and suboptimal 25(OH)D levels (< 50 nmol/l) were found in 23.5% (n = 20) and 52% (n = 44) of children, respectively. Younger children (< 13 years) with CD with suboptimal 25(OH)vitD (< 50 nmol/l) had the greatest frequency of sarcopenia (57.1%) (p = 0.004). Sarcopenia was prevalent in newly diagnosed, young children with CD with vitD deficiency.

Indexed as

Inflammatory Bowel DiseasesSarcopeniaVitamin D DeficiencyAdolescentChildChild, PreschoolCohort StudiesHumansNutritional StatusRisk FactorsVitamin DVitamin D

Identifiers

PMID29391593
OpenAlexW2790201398

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.