ArticleScientific reports2018
Whole metagenome sequencing reveals links between mosquito microbiota and insecticide resistance in malaria vectors.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers.
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Who cites it
89 citing papers in PubMed.
- Mosquito-based malaria control through genetic, microbial and immunological innovations.Nature reviews. Microbiology · 2026Review
- The Adult Aedes aegypti Bacterial Microbiota is Robust to Infection with the Obligate Microsporidian Parasite Edhazardia aedis.Environmental microbiology · 2026Article
- Operationalising Environmental DNA (eDNA) Detection of Major Malaria Vector Species in Ghana.Molecular ecology resources · 2026Article
- The XylC-mediated aromatic metabolic network modulates the metabolic response of Pseudomonas aeruginosa to deltamethrin.BMC microbiology · 2026Article
- Crop: The Black Box of Mosquito Vector Fitness.Insects · 2026Review
- Bacterial community structure and diversity of common mosquito species in Chengdu: Insights from PacBio third-generation sequencing and public health implications.PLoS neglected tropical diseases · 2026Article
- Insecticide resistance profiles of Anopheles arabiensis and relationship with Microsporidia MB infection in two rice agroecosystems in Kenya.Parasites & vectors · 2026Article
- Ecological and engineered modulation of the mosquito microbiome: mechanisms, vector competence, and translational prospects for disease control.Frontiers in microbiology · 2026Review
- FirstCurrent research in parasitology & vector-borne diseases · 2026Article
- Transplant of cryopreserved mosquito gut microbiota reveals strain-specific patterns of microbial acquisition and assembly.ISME host microbe · 2026Article
- PoolSeq Genome-Wide Association Studies and Microbial Signature Analyses Identify Novel Candidates Associated With Pyrethroid Resistance Evolution in Anopheles funestus in Cameroon.Molecular ecology · 2026Article
- Diversity of culturable gut bacteria and their role in conferring resistance to alpha-cypermethrin in field populations ofFrontiers in microbiology · 2026Article
- Environmental persistence and transmission dynamics ofApplied and environmental microbiology · 2025Article
- Impact of insecticide resistance on controlling mosquito vectors and its potential contribution to behavioural modifications.Malaria journal · 2025Review
- Bacterial community composition and diversity associated with developmental stages of Anopheles subpictus.International microbiology : the official journal of the Spanish Society for Microbiology · 2025Article
- Assessing gut microbiota diversity and functional potential in resistant and susceptible strains of the mediterranean fruit fly.Scientific reports · 2025Article
- Leveraging microbial ecology for mosquito-borne disease control.Trends in parasitology · 2025Review
- The Effect of Larval Exposure to Plastic Pollution on the Gut Microbiota of the Major Malaria Vector Anopheles arabiensis Patton (Diptera: Culicidae).Environmental microbiology reports · 2025Article
- Evidence of microbiome contribution to the escalation of pyrethroid resistance in the major malaria vectors Anopheles gambiae s.s. and Anopheles funestus s.s.BMC microbiology · 2025Article
- Microbiome evolution plays a secondary role in host rapid adaptation.bioRxiv : the preprint server for biology · 2025Article
29 more citing papers are in PubMed but not listed here.
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5 authors.
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Abstract
In light of the declining global malaria burden attained largely due to insecticides, a deeper understanding of the factors driving insecticide resistance is needed to mitigate its growing threat to malaria vector control programs. Following evidence of microbiota-mediated insecticide resistance in agricultural pests, we undertook a comparative study of the microbiota in mosquitoes of differing insecticide resistance status. The microbiota of wild-caught Anopheles albimanus, an important Latin American malaria vector, that were resistant (FEN_Res) or susceptible (FEN_Sus) to the organophosphate (OP) insecticide fenitrothion were characterized and compared using whole metagenome sequencing. Results showed differing composition of the microbiota and its functions between FEN_Res and FEN_Sus, with significant enrichment of OP-degrading bacteria and enzymes in FEN_Res compared to FEN_Sus. Lower bacterial diversity was observed in FEN_Res compared to FEN_Sus, suggesting the enrichment of bacterial taxa with a competitive advantage in response to insecticide selection pressure. We report and characterize for the first time whole metagenomes of An. albimanus, revealing associations between the microbiota and phenotypic resistance to the insecticide fenitrothion. This study lays the groundwork for further investigation of the role of the mosquito microbiota in insecticide resistance.
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