Evidence map›Paper›PMID 29391345›Full record

ArticleJMIR medical informatics2018

Automated Information Extraction on Treatment and Prognosis for Non-Small Cell Lung Cancer Radiotherapy Patients: Clinical Study.

Shuai Zheng, Salma K Jabbour, Shannon E O'Reilly, James J Lu, Lihua Dong, Lijuan Ding, Ying Xiao, Ning Yue, Fusheng Wang, Wei Zou

Open access · goldAbstract read
In one paragraph

Article in JMIR medical informatics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Shuai ZhengDepartment of Biomedical Informatics, Emory University, Atlanta, GA, United States.ORCID http://orcid.org/0000-0002-8090-9278
Salma K JabbourDepartment of Radiation Oncology, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, United States.ORCID http://orcid.org/0000-0001-8200-5371
Shannon E O'ReillyPenn Medicine, Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA, United States.ORCID http://orcid.org/0000-0002-7766-8979
James J LuDepartment of Mathematics and Computer Science, Emory University, Atlanta, GA, United States.ORCID http://orcid.org/0000-0001-7888-7412
Lihua DongDepartment of Radiation Oncology, The First Hospital, Changchun, China.ORCID http://orcid.org/0000-0002-9211-8369
Lijuan DingDepartment of Radiation Oncology, The First Hospital, Changchun, China.ORCID http://orcid.org/0000-0002-9156-9328
Ying XiaoPenn Medicine, Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA, United States.ORCID http://orcid.org/0000-0001-8558-6394
Ning YueDepartment of Radiation Oncology, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, United States.ORCID http://orcid.org/0000-0002-7885-7368
Fusheng Wang *Department of Biomedical Informatics, Stony Brook University, Stony Brook, NY, United States.ORCID http://orcid.org/0000-0002-9369-9361
Wei Zou *Penn Medicine, Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA, United States.ORCID http://orcid.org/0000-0001-5307-4685
Penn Center for AIDS Research · USEmory University · USJilin University · CNRutgers, The State University of New Jersey · USStony Brook University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn outcome studies of oncology patients undergoing radiation, researchers extract valuable information from medical records generated before, during, and after radiotherapy visits, such as survival data, toxicities, and complications. Clinical studies rely heavily on these data to correlate the treatment regimen with the prognosis to develop evidence-based radiation therapy paradigms. These data are available mainly in forms of narrative texts or table formats with heterogeneous vocabularies. Manual extraction of the related information from these data can be time consuming and labor intensive, which is not ideal for large studies.

objectiveThe objective of this study was to adapt the interactive information extraction platform Information and Data Extraction using Adaptive Learning (IDEAL-X) to extract treatment and prognosis data for patients with locally advanced or inoperable non-small cell lung cancer (NSCLC).

methodsWe transformed patient treatment and prognosis documents into normalized structured forms using the IDEAL-X system for easy data navigation. The adaptive learning and user-customized controlled toxicity vocabularies were applied to extract categorized treatment and prognosis data, so as to generate structured output.

resultsIn total, we extracted data from 261 treatment and prognosis documents relating to 50 patients, with overall precision and recall more than 93% and 83%, respectively. For toxicity information extractions, which are important to study patient posttreatment side effects and quality of life, the precision and recall achieved 95.7% and 94.5% respectively.

conclusionsThe IDEAL-X system is capable of extracting study data regarding NSCLC chemoradiation patients with significant accuracy and effectiveness, and therefore can be used in large-scale radiotherapy clinical data studies.

Indexed as

chemoradiation treatmentinformation extractioninformation storage and retrievalnatural language processingnon–small cell lungoncologyprognosis

Identifiers

PMID29391345
PMCPMC5814605
OpenAlexW2785517012

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.