ArticleThe Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology2018
The relationship of alanine aminotransferase to metabolic syndrome in a Korean population.
Article in The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Aging and liver health: liver chemistries and associated factors in community-dwelling older adults.BMC geriatrics · 2025Article
- Morbid liver manifestations are intrinsically bound to metabolic syndrome and nutrient intake based on a machine-learning cluster analysis.Frontiers in endocrinology · 2022Article
- Association of total bilirubin and indirect bilirubin content with metabolic syndrome among Kazakhs in Xinjiang.BMC endocrine disorders · 2020Article
- Measurement of the Combined Levels of Serum Uric Acid and Alanine Aminotransferase and the Risk of Metabolic Syndrome in a Population Aged 60 Years or More in Northeastern China.Medical science monitor : international medical journal of experimental and clinical research · 2020Article
- The Association between Metabolic Syndrome and Elevated Alanine Aminotransferase Levels in an Indigenous Population in Northern Taiwan: A Community-Based and Cross-Sectional Study.Evidence-based complementary and alternative medicine : eCAM · 2020Article
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Abstract
BACKGROUND/
aimsAlthough associations between serum alanine aminotransferase and metabolic syndrome are well-recognized in Western countries, only a limited number of prospective studies have been performed in Asian populations. The aim of the study was to cross-sectionally and longitudinally examine whether serum alanine aminotransferase levels are associated with metabolic syndrome and its associated components in a Korean population. MATERIALS AND
methodsA total of 31,832 subjects who received health screenings were included in cross-sectional analyses; a subgroup of 4.070 subjects without metabolic syndrome at baseline was included in the longitudinal analyses. The metabolic syndrome definition was based on the National Cholesterol Education Program Third Adult Treatment Panel criteria with modification on waist circumference cut-off to be more appropriate for an Asian population.
resultsIn the cross-sectional analyses, serum alanine aminotransferase is positively associated with metabolic syndrome and its components. In the longitudinal analyses, the prevalence of metabolic syndrome increased across serum alanine aminotransferase quartiles in a dose-dependent manner after extensive adjustments (hazard ratios were 1.000, 1.609, 2.601, and 3.015 for quartiles, 1 through quartile 4; P for trend<0.001).
conclusionOur study confirmed a positive association between components of metabolic syndrome and elevated serum alanine aminotransferase in a Korean population.
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