Evidence map›Paper›PMID 29391039›Full record

ArticleBMC research notes2018

Incidence of diabetes mellitus-related comorbidities among patients attending two major HIV clinics in Botswana: a 12-year retrospective cohort study.

Goabaone Rankgoane-Pono, Jose Gaby Tshikuka, Mgaywa Gilbert Mjungu Damas Magafu, Tiny Masupe, Mooketsi Molefi, Shimeles Genna Hamda, Vincent Setlhare, Roy Tapera, Bontle Mbongwe

Abstract read
In one paragraph

Article in BMC research notes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Goabaone Rankgoane-PonoDepartment of Family Medicine and Public Health, Faculty of Medicine, University of Botswana, Gaborone, Botswana.
Jose Gaby TshikukaDepartment of Family Medicine and Public Health, Faculty of Medicine, University of Botswana, Gaborone, Botswana. jtshikuka@hotmail.com.
Mgaywa Gilbert Mjungu Damas MagafuDepartment of Family Medicine and Public Health, Faculty of Medicine, University of Botswana, Gaborone, Botswana.
Tiny MasupeDepartment of Family Medicine and Public Health, Faculty of Medicine, University of Botswana, Gaborone, Botswana.
Mooketsi MolefiDepartment of Family Medicine and Public Health, Faculty of Medicine, University of Botswana, Gaborone, Botswana.
Shimeles Genna HamdaDepartment of Family Medicine and Public Health, Faculty of Medicine, University of Botswana, Gaborone, Botswana.
Vincent SetlhareDepartment of Family Medicine and Public Health, Faculty of Medicine, University of Botswana, Gaborone, Botswana.
Roy TaperaSchool of Public Health, Faculty of Health Sciences, University of Botswana, Private Bag 0022, Gaborone, Botswana.
Bontle MbongweSchool of Public Health, Faculty of Health Sciences, University of Botswana, Private Bag 0022, Gaborone, Botswana.

Funding

U.S. Department of Health and Human Services (HHS) T84HA22125
6 · The paper itself

Abstract

objectivesExposure to combination antiretroviral therapy (cART) is associated with the development of diabetes mellitus related comorbidities (DRCs). This study aims to: (i) estimate the incidence of DRCs among cART recipients, (ii) assess the time-to-event (development of DRC) and, (iii) compare survival function between recipients on first-line regimen and those on second-, third-line cART regimen.

resultsThe incidence of DRCs was 26.8/1000 person-years, with total time of exposure of 3316 person-years. The average time to event for all the three regimens was 11.72 ± 0.20 years. The first-line cART regimen had a shorter mean ± SE of 10.59 ± 0.26 years to the event compared to 12.69 ± 0.24 years for the second-, third-line cART regimen. Recipients on the first-line had a shorter survival than recipients on second-, third-line cART (Log-rank X

Indexed as

AdultAnti-HIV AgentsAntiretroviral Therapy, Highly ActiveBotswanaCD4 Lymphocyte CountComorbidityDiabetes Mellitus, Type 2FemaleHIV-1HIV InfectionsHumansIncidenceMaleMiddle AgedRetrospective StudiesViral LoadAnti-HIV AgentsBotswanaCombination antiretroviral therapyDiabetes-related comorbiditiesIncidencePLHIV

Identifiers

PMID29391039
PMCPMC5796438

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.