Evidence map›Paper›PMID 29390446›Full record

ArticleMedicine2017

Hepatic angiosarcomatous transformation of a mediastinal germinal cell tumor: A care case report.

Giuseppe Corrias, Joanna G Escalon, Laura Tang, Serena Monti, Luca Saba, Lorenzo Mannelli

Erratum issuedOpen access · goldAbstract readCase Reports
In one paragraph

Article in Medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Giuseppe CorriasDepartment of Radiology, Memorial Sloan Kettering Cancer Center, York Avenue, New York, NY, USA Department of Radiology, University of Cagliari, via Università, Cagliari, Italy Department of Radiology, New York-Presbyterian/Weill Cornell Medical Center, New York, NY Department of Radiology, University of Colorado, Aurora, CO Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA IRCCS SDN, Naples, Italy.
Joanna G Escalon
Laura Tang
Serena Monti
Luca Saba
Lorenzo Mannelli
University of Cagliari · ITCornell University · USIstituti di Ricovero e Cura a Carattere Scientifico · ITMemorial Sloan Kettering Cancer Center · USUniversity of Colorado Denver · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

rationaleMediastinal nonseminomatous germ cell tumor (NSGCT) is an uncommon entity. Metastatic hepatic sarcomatous transformation is rare. PATIENT CONCERNS: We report a 24-year-old man with no previous related medical history presented with chest pain and left arm numbness. DIAGNOSES: The x-ray showed an anterior mediastinal mass. The chest computed tomography (CT) confirmed the presence of a mildly enhancing mass in the same location, without invasion of any vascular structure. A CT-guided biopsy was performed, revealing a primary mediastinal nonseminomatous germ cell tumor (NSGCT), yolk sac histology, with areas of somatic transformation to malignant nerve sheath tumor. After surgery patient was followed-up with imaging. Two years later a CT scan showed a new hepatic hyper vascular lesion, confirmed by a subsequent magnetic resonance imaging (MRI) and positron emission tomography (PET) scan. A CT-guided biopsy revealed a hepatic metastatic transformation to angiosarcoma of the primitive NSGCT.

interventionsThe patient went on to received palliative chemotherapy. OUTCOMES: The patient is being followed-up regularly at the outpatient department. LESSONS: Because of the potential of metastatic sarcoma arising from germ cell tumors, these patients should undergo periodical follow-up, with periodical scans. PET\CT scan might have a role in the follow-up of these patients.

Indexed as

Cell Transformation, NeoplasticDiagnostic ImagingHemangiosarcomaHumansLiver NeoplasmsMaleMediastinal NeoplasmsNeoplasms, Germ Cell and EmbryonalYoung Adult

Identifiers

PMID29390446
PMCPMC5758148
OpenAlexW2780687143

What OpenQuestion holds

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LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.