Observational studyMedicine2017
Risk factors for death in septic shock: A retrospective cohort study comparing trauma and non-trauma patients.
Observational study in Medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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Who cites it
16 citing papers in PubMed.
- Impact of Treatment with Antioxidants as an Adjuvant to Standard Therapy in Patients with Septic Shock: Analysis of the Correlation between Cytokine Storm and Oxidative Stress and Therapeutic Effects.International journal of molecular sciences · 2023Trial
- Association between early prophylactic heparin therapy and mortality in patients with septic shock secondary to respiratory infections: analysis based on MIMIC-IV database.BMC infectious diseases · 2025Article
- Bundle compliance patterns in septic shock and their association with patient outcomes: an unsupervised cluster analysis.Internal and emergency medicine · 2025Article
- Clinical Efficacy of Continuous Renal Replacement Therapy in Patients with Pulmonary Tuberculosis Complicated with Sepsis: A Retrospective Observational Study.Infection and drug resistance · 2025Article
- Epidemiological characteristics and impact of sepsis on survival after osteoporotic pelvic fracture in Austria.Scientific reports · 2024Article
- Predictors of Treatment Failure and Mortality among Patients with Septic Shock Treated with Meropenem in the Intensive Care Unit.The Malaysian journal of medical sciences : MJMS · 2024Article
- Clinical Characteristics and Nomogram for Predicting Mortality in Patients with Postoperative Bloodstream Infection in Surgical Intensive Care Unit.International journal of clinical practice · 2024Article
- Association Between Multidrug-Resistant Bacteria and Mortality in Critically Ill Patients.Advances in therapy · 2023Observational
- Septic Shock: Management and Outcomes.Cureus · 2022Review
- What Do We Know about Early Management of Sepsis and Septic Shock in Polish Hospitals? A Questionnaire Study.Healthcare (Basel, Switzerland) · 2021Article
- The therapeutic efficacy of adjunct therapeutic plasma exchange for septic shock with multiple organ failure: a single-center experience.Critical care (London, England) · 2020Observational
- Information Bottleneck for Estimating Treatment Effects with Systematically Missing Covariates.Entropy (Basel, Switzerland) · 2020Article
- Can the fate be cheated? Septic shock in the course of an abdominal multi-organ trauma - a case report.Anaesthesiology intensive therapy · 2020Article
- The Role of Host-Generated HFrontiers in cellular and infection microbiology · 2020Review
- Association of Age With Short-term and Long-term Mortality Among Patients Discharged From Intensive Care Units in France.JAMA network open · 2019Observational
- Management of vasopressor induced ischemia.Journal of orthopaedicsArticle
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to compare septic shock directly associated-mortality between severe trauma patients and nontrauma patients to assess the role of comorbidities and age. We conducted a retrospective study in an intensive care unit (ICU) (15 beds) of a university hospital (928 beds). From January 2009 to May 2015, we reviewed 2 anonymized databases including severe trauma patients and nontrauma patients. We selected the patients with a septic shock episode. Among 385 patients (318 nontrauma patients and 67 severe trauma patients), the ICU death rate was 43%. Septic shock was directly responsible for death among 35% of our cohort, representing 123 (39%) nontrauma patients and 10 (15%) trauma patients (P < 0.0). A sequential organ failure assessment score above 12 (odds ratio [OR]: 6.8; 95% confident interval (CI) [1.3-37], P = 0.025) was independently associated with septic shock associated-mortality, whereas severe trauma was a protective factor (OR: 0.26; 95% CI [0.08-0.78], P = 0.01). From these independent risk factors, we determined the probability of septic shock associated-mortality. The receiver-operating characteristics curve has an area under the curve at 0.76 with sensitivity of 55% and specificity of 86%. Trauma appears as a protective factor, whereas the severity of organ failure has a major role in the mortality of septic shock. However, because of the study's design, unmeasured confounding factors should be taken into account in our findings.
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