Evidence map›Paper›PMID 29390321›Full record

ArticleMedicine2017

Case report: Ribavirin and vitamin A in a severe case of measles.

Amandine Bichon, Camille Aubry, Lucas Benarous, Hortense Drouet, Christine Zandotti, Philippe Parola, Jean-Christophe Lagier

Open access · goldAbstract readCase Reports
In one paragraph

Article in Medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Review
  3. Severe measles with pneumonitis in an immunocompetent adult.Clinical medicine (London, England) · 2024
    Article
  4. Measles: Contemporary considerations for the emergency physician.Journal of the American College of Emergency Physicians open · 2023
    Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Amandine BichonAix Marseille Univ, CNRS 7278, IRD 198, INSERM 1095, AP-HM, URMITE, IHU Méditerranée-Infection, 19-21 Boulevard Jean Moulin, Marseille Cedex 5 Assistance Publique Hôpitaux de Marseille, CHU Timone, Service de réanimation médicale, Marseille, France.
Camille Aubry
Lucas Benarous
Hortense Drouet
Christine Zandotti
Philippe Parola
Jean-Christophe Lagier
Méditerranée Infection Foundation · FRUnité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

rationaleDespite a vaccine being widely available, measles continues to occur frequently, with sometimes lethal consequences. PATIENTS CONCERNS: The mortality rate reaches 35% and measles represents 44% of the 1.4 million deaths which are due to preventable diseases. Severe forms of measles are reported, mainly in young, unvaccinated adults, and in specific populations. The risk factors for severe measles include no or incomplete vaccination and vitamin A deficiency. Apart from secondary measles-related infections, severe measles is mainly represented by neurological, respiratory, and digestive symptoms. DIAGNOSES: Strengthening the hypothesis that there is a link between vitamin A deficiency and severe measles in this paper we report the case of a 25-year-old unvaccinated man hospitalized for severe and complicated measles. OUTCOMES: The evolution was good after administration of intramuscular vitamin A as well as intravenous ribavirin. LESSONS: Measles remains a fatal and serious disease. The early use of ribavirin and vitamin A shows significant improvements regarding morbimortality and should be systematic in severe cases.

Indexed as

AdultAntiviral AgentsHumansMaleMeaslesRibavirinVitamin AAntiviral AgentsRibavirinVitamin A

Identifiers

PMID29390321
PMCPMC5815733
OpenAlexW2773140990

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.