Evidence map›Paper›PMID 29390004›Full record

ArticlePLoS computational biology2018

The development and application of bioinformatics core competencies to improve bioinformatics training and education.

Nicola Mulder, Russell Schwartz, Michelle D Brazas, Cath Brooksbank, Bruno Gaeta, Sarah L Morgan, Mark A Pauley, Anne Rosenwald, Gabriella Rustici, Michael Sierk and 2 more

Abstract read
In one paragraph

Article in PLoS computational biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed.

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8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Nicola MulderComputational Biology Division, Department of Integrative Biomedical Sciences, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.ORCID 0000-0003-4905-0941
Russell SchwartzDepartment of Biological Sciences and Computational Biology Department, Carnegie Mellon University, Pittsburgh, Pennsylvania, United States of America.ORCID 0000-0002-4970-2252
Michelle D BrazasOntario Institute for Cancer Research, Toronto, Canada.ORCID 0000-0001-8150-4531
Cath BrooksbankEMBL-EBI, Wellcome Genome Campus, Hinxton, Cambridge, United Kingdom.
Bruno GaetaSchool of Computer Science and Engineering, University of New South Wales, Sydney, Australia.ORCID 0000-0003-4723-4982
Sarah L MorganEMBL-EBI, Wellcome Genome Campus, Hinxton, Cambridge, United Kingdom.
Mark A PauleySchool of Interdisciplinary Informatics, University of Nebraska at Omaha, Omaha, Nebraska, United States of America.ORCID 0000-0003-1308-0321
Anne RosenwaldDepartment of Biology, Georgetown University, Washington, DC, United States of America.
Gabriella RusticiDepartment of Genetics, University of Cambridge, Cambridge, United Kingdom.ORCID 0000-0003-3085-1271
Michael SierkSaint Vincent College, Latrobe, Pennsylvania, United States of America.ORCID 0000-0002-0657-0288
Tandy WarnowDepartment of Computer Science and Department of Bioengineering, University of Illinois, Urbana-Champaign, Champaign, United States of America.
Lonnie WelchSchool of Electrical Engineering and Computer Science, Ohio University, Athens, Ohio, United States of America.

Funding

H3ABioNet: a sustainable African Bioinformatics Network for H3AfricaU41HG006941 · NHGRI · UNIVERSITY OF CAPE TOWN · PI MULDER, NICOLA · 2012 to 2017
$14.8M
H3ABioNet: informatics solutions for H3AfricaU24HG006941 · NHGRI · UNIVERSITY OF CAPE TOWN · PI MULDER, NICOLA · 2017 to 2021
$12.9M
MECHANISMS ENSURING SEQUENCE-DEPENDENT GPCR RECYCLINGR01GM117425 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI PUTHENVEEDU, MANOJKUMAR A · 2016 to 2020
$1.5M
DECONVOLUTION OF CLONAL HETEROGENEITY FROM BULK AND SINGLE-CELL VARIATION DATAR21CA216452 · NCI · CARNEGIE-MELLON UNIVERSITY · PI SCHWARTZ, RUSSELL S · 2017 to 2018
$342k
NCI NIH HHS R21 CA216452NHGRI NIH HHS U24 HG006941NHGRI NIH HHS U41 HG006941NIGMS NIH HHS R01 GM117425NIH HHS R01GM117425NIH HHS R21CA216452
6 · The paper itself

Abstract

Bioinformatics is recognized as part of the essential knowledge base of numerous career paths in biomedical research and healthcare. However, there is little agreement in the field over what that knowledge entails or how best to provide it. These disagreements are compounded by the wide range of populations in need of bioinformatics training, with divergent prior backgrounds and intended application areas. The Curriculum Task Force of the International Society of Computational Biology (ISCB) Education Committee has sought to provide a framework for training needs and curricula in terms of a set of bioinformatics core competencies that cut across many user personas and training programs. The initial competencies developed based on surveys of employers and training programs have since been refined through a multiyear process of community engagement. This report describes the current status of the competencies and presents a series of use cases illustrating how they are being applied in diverse training contexts. These use cases are intended to demonstrate how others can make use of the competencies and engage in the process of their continuing refinement and application. The report concludes with a consideration of remaining challenges and future plans.

Indexed as

CurriculumEducation, GraduateAdvisory CommitteesAfricaAlgorithmsComputational BiologyGenetic Predisposition to DiseaseIllinoisNew South WalesOhioPennsylvaniaSoftwareSurveys and QuestionnairesSystems BiologyUnited KingdomUniversities

Identifiers

PMID29390004
PMCPMC5794068

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.